| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | group | BEFREE | Besides, proinflammatory cytokines such as, IFN-γ, TNF-α, IL-6, and IL-17 were significantly diminished in the serum and spinal cord of EAE mice receiving HIV-1 Tat clade B and C. Conversely, anti-inflammatory cytokines, including IL-10 and IL-4 were elevated in the serum and spinal cord of EAE mice receiving HIV Tat clade B and C when compared with the control group. | 31830622 | 2020 | ||||
|
0.080 | Biomarker | group | BEFREE | Nonobese diabetic severe combined immunodeficient γc<sup>-/-</sup> (NSG) mice received intraperitoneally allergen-reactive PBMC from birch pollen-allergic patients together with birch pollen extract and human IL-4. | 29159964 | 2018 | ||||
|
0.080 | Biomarker | group | BEFREE | Finally, we show that administration of IL-4 to immunodeficient mice to regulate inflammation by induction of type 2 responses also restores parasite development. | 24130499 | 2013 | ||||
|
0.080 | GeneticVariation | group | BEFREE | However, application of Bonferroni correction identified only two SNPs i.e., TNF-α -238 AG and IL-4 -33 TT to be significantly associated with the acquisition of HIV. | 23867674 | 2013 | ||||
|
0.080 | Biomarker | group | BEFREE | IL-4 increases Simian immunodeficiency virus replication despite enhanced SIV immune responses in infected rhesus macaques. | 11943227 | 2002 | ||||
|
0.080 | AlteredExpression | group | BEFREE | The antitumor activity of IL-4 toxin was tested in vitro by cytotoxicity assays and in vivo in a xenograft model in immunodeficient animals. | 10965493 | 2000 | ||||
|
0.080 | AlteredExpression | group | BEFREE | Interleukin (IL)-2, IL-4 and IL-5 mRNA were not detected in any LN or PB sample from HIV-infected children. | 11114129 | 2000 | ||||
|
0.080 | Biomarker | group | BEFREE | The amounts of both IFN-gamma and IL-4 were decreased in the HIV-infected population. | 9607833 | 1998 |