Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
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0.540 | Biomarker | phenotype | CTD_human | IL-6, IL-8 and monocyte chemoattractant protein-1 (MCP-1), quantified by ELISA and by gene expression analysis using a low-density array allowing the evaluation of expression level for 46 genes relevant of the intestinal inflammation and functional metabolism. | 20816778 | 2010 | ||||
|
0.540 | Biomarker | phenotype | CTD_human | Lidocaine attenuates monocyte chemoattractant protein-1 production and chemotaxis in human monocytes: possible mechanisms for its effect on inflammation. | 14570645 | 2003 | ||||
|
0.540 | Biomarker | phenotype | CTD_human | Didecyldimethylammonium chloride induces pulmonary inflammation and fibrosis in mice. | 19762220 | 2010 | ||||
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0.540 | GeneticVariation | phenotype | LHGDN | Inheritance of the -2518 MCP-1 G allele, which appears to affect hepatic MCP-1 expression, may predispose HCV patients to more severe hepatic inflammation and fibrosis. | 14517792 | 2003 | ||||
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0.540 | Biomarker | phenotype | LHGDN | Therefore, MCP-1 may represent a molecular link in the negative cross-talk between adipose tissue and skeletal muscle assigning a completely novel important role to MCP-1 besides inflammation. | 16439461 | 2006 | ||||
|
0.540 | Biomarker | phenotype | LHGDN | Monocyte chemotactic protein-1 is thus a therapeutic target, and may represent an important factor linking adipose tissue inflammation, obesity and type 2 diabetes. | 17495598 | 2007 | ||||
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0.540 | Biomarker | phenotype | LHGDN | The results suggest that HHV-8-induced MCP-1 may play an important role in promoting inflammation and pathogenic angiogenesis typical of HHV-8-associated lesions. | 17138827 | 2007 | ||||
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0.540 | Biomarker | phenotype | RGD | The increased BP was related to increased aortic inflammation (tumor necrosis factor [TNF]-α; nitric oxide synthase [iNOS], COX-2 and MCP-1 protein expression) and elevated angiotensin II levels in alcohol-treated group compared to control. | 20921064 | 2011 |