Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10082
Gene Symbol: GPC6
GPC6
0.100 GeneticVariation phenotype GWASDB Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans. 22791750 2012
Entrez Id: 6307
Gene Symbol: MSMO1
MSMO1
0.100 GeneticVariation phenotype GWASDB Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans. 22791750 2012
Entrez Id: 100128714
Gene Symbol: LINC02346
LINC02346
0.100 GeneticVariation phenotype GWASCAT Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study. 21901158 2011
Entrez Id: 100128714
Gene Symbol: LINC02346
LINC02346
0.100 GeneticVariation phenotype GWASDB Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study. 21901158 2011
Entrez Id: 1793
Gene Symbol: DOCK1
DOCK1
0.100 GeneticVariation phenotype GWASCAT Genome-Wide Meta-analysis of Gene-Environmental Interaction for Insulin Resistance Phenotypes and Breast Cancer Risk in Postmenopausal Women. 30327367 2019
Entrez Id: 6307
Gene Symbol: MSMO1
MSMO1
0.100 GeneticVariation phenotype GWASCAT Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans. 22791750 2012
Entrez Id: 54039
Gene Symbol: PCBP3
PCBP3
0.100 GeneticVariation phenotype GWASDB Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study. 21901158 2011
Entrez Id: 54039
Gene Symbol: PCBP3
PCBP3
0.100 GeneticVariation phenotype GWASCAT Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study. 21901158 2011
Entrez Id: 3643
Gene Symbol: INSR
INSR
0.600 Biomarker phenotype CTD_human Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction. 10949030 2000
Entrez Id: 3643
Gene Symbol: INSR
INSR
0.600 Biomarker phenotype HPO
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
0.600 Biomarker phenotype RGD Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle. 10426374 1999
Entrez Id: 3643
Gene Symbol: INSR
INSR
0.600 Biomarker phenotype CTD_human To evaluate whether hyperglycaemia in two lean patients with primary severe insulin resistance due to insulin receptor (IR) mutations and diabetes mellitus could be reduced by supplement of rosiglitazone for 180 days and secondary, to evaluate the effects on plasma NEFA, TG, Apo B, PAI-1 and serum insulin. 11887975 2001
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
0.600 Biomarker phenotype CTD_human [Cell biological mechanism involved in the effect of sodium selenite on improving insulin sensitivity]. 14714311 2003
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1
0.600 Biomarker phenotype HPO
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
0.500 Biomarker phenotype CTD_human Arsenic induces diabetic effects through beta-cell dysfunction and increased gluconeogenesis in mice. 25367288 2014
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Biomarker phenotype CTD_human In conclusion, we described a significant association between eNOS gene polymorphisms and type 2 diabetes, suggesting a new genetic susceptibility factor for hyperinsulinemia, insulin resistance, and type 2 diabetes. 12716763 2003
Entrez Id: 5562
Gene Symbol: PRKAA1
PRKAA1
0.500 Biomarker phenotype CTD_human AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol. 19934007 2010
Entrez Id: 3953
Gene Symbol: LEPR
LEPR
0.500 Biomarker phenotype CTD_human Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. 20567778 2010
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2
0.500 Biomarker phenotype RGD Attenuation of insulin resistance by chronic beta2-adrenergic agonist treatment possible muscle specific contributions. 11510954 2001
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.500 Biomarker phenotype CTD_human These data highlight the potential utility of eNOS gene therapy in the treatment of hypertension and insulin resistance. 19008412 2009
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.500 Biomarker phenotype RGD Generation of leptin-deficient Lepmkyo/Lepmkyo rats and identification of leptin-responsive genes in the liver. 23800849 2013
Entrez Id: 3952
Gene Symbol: LEP
LEP
0.500 Biomarker phenotype CTD_human Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. 11342529 2001
Entrez Id: 948
Gene Symbol: CD36
CD36
0.500 Biomarker phenotype CTD_human Transgenic expression of Cd36 in the new lines was associated with significantly decreased serum fatty acids, amelioration of insulin resistance and glucose intolerance but failed to induce any consistent changes in blood pressure as measured by radiotelemetry. 14640889 2003
Entrez Id: 6720
Gene Symbol: SREBF1
SREBF1
0.500 Biomarker phenotype RGD Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis. 17241878 2007
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.500 Biomarker phenotype CTD_human In addition, constant darkness-induced circadian misalignment in mice decreases hepatic BMAL1 and SIRT1 levels and induces IR, which can be dramatically reversed by resveratrol. 24442997 2014