Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion. | 31316209 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Publisher Correction: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion. | 31367045 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Still more targets such as CLL-1, EGFR, NKG2D and mesothelin are being directed in CAR-T cell trials for leukemia and solid tumors. | 31703740 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Thus, NKG2D-Fc-ADCC potently enhances NK antileukemia reactivity despite the inevitable reduction of activating signals upon binding to NKG2DL and may constitute an attractive means for immunotherapy of leukemia. | 25046567 | 2015 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Together, we provide comprehensive data on the relevance of NKG2D/NKG2DL expression, release, and function for NK reactivity in leukemia, which exemplifies the mechanisms underlying NKG2D-mediated tumor immunosurveillance and escape. | 22730533 | 2012 | ||||
|
0.090 | Biomarker | disease | BEFREE | Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate. | 19151770 | 2009 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | In this study, we investigated the effects of IL-18 on the expression of NKG2D ligands in leukemia cells. | 18706445 | 2008 | ||||
|
0.090 | Biomarker | disease | BEFREE | Here, we have studied the role of NKG2D and natural cytotoxicity receptors (NCRs) in the recognition of human leukemia. | 15657183 | 2005 | ||||
|
0.090 | Biomarker | disease | BEFREE | Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia. | 12714493 | 2003 |