Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10112
Gene Symbol: KIF20A
KIF20A 		0.010 Biomarker disease BEFREE RAB6KIFL maps within the smallest commonly deleted segment in myeloid leukemias characterized by a deletion of 5q; however, we detected no mutations of RAB6KIFL in malignant myeloid disorders with loss of 5q. 10806357 2000
Entrez Id: 8028
Gene Symbol: MLLT10
MLLT10 		0.030 Biomarker disease BEFREE AF10 has been reported to be re-arranged with genes other than MLL leading to the same phenotype, a myeloid leukaemia. 10860745 2000
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.010 GeneticVariation disease BEFREE Glutathione S-transferase polymorphisms in children with myeloid leukemia: a Children's Cancer Group study. 10868689 2000
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A 		0.400 Biomarker disease BEFREE MLL amplification in myeloid leukemias: A study of 14 cases with multiple copies of 11q23. 10918392 2000
Entrez Id: 53335
Gene Symbol: BCL11A
BCL11A 		0.020 Biomarker disease BEFREE Evi9, a common site of retroviral integration in BXH2 murine myeloid leukemias, encodes a C2H2 zinc finger protein and is overexpressed in these leukemic cells. 11161790 2000
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1 		0.100 Biomarker disease BEFREE AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia. 11283671 2001
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		0.020 Biomarker disease BEFREE PIK3CG is unlikely to act as a recessive TSG in myeloid leukemias with monosomy 7. 11756194 2002
Entrez Id: 7474
Gene Symbol: WNT5A
WNT5A 		0.010 Biomarker disease BEFREE Wnt5a hemizygous mice develop myeloid leukemias and B cell lymphomas that are clonal in origin and display loss of Wnt5a function in tumor tissues. 14667502 2003
Entrez Id: 4297
Gene Symbol: KMT2A
KMT2A 		0.400 AlteredExpression disease BEFREE MLL fusion proteins are oncogenic transcription factors that are associated with aggressive lymphoid and myeloid leukemias. 14701735 2004
Entrez Id: 51352
Gene Symbol: WT1-AS
WT1-AS 		0.010 Biomarker disease BEFREE WT1 as a universal marker for minimal residual disease detection and quantification in myeloid leukemias and in myelodysplastic syndrome. 15179007 2004
Entrez Id: 10874
Gene Symbol: NMU
NMU 		0.010 Biomarker disease BEFREE Neuromedin U: a Myb-regulated autocrine growth factor for human myeloid leukemias. 15187020 2004
Entrez Id: 4928
Gene Symbol: NUP98
NUP98 		0.050 AlteredExpression disease BEFREE NUP98-HOXA9 expression promoted the onset of retrovirus-induced BXH2 myeloid leukemia. 15454493 2005
Entrez Id: 25865
Gene Symbol: PRKD2
PRKD2 		0.010 AlteredExpression disease LHGDN Protein kinase D2 mediates activation of nuclear factor kappaB by Bcr-Abl in Bcr-Abl+ human myeloid leukemia cells. 15604256 2004
Entrez Id: 4170
Gene Symbol: MCL1
MCL1 		0.030 AlteredExpression disease LHGDN MCL1 was upregulated by PMA in THP-1 and U937 myeloid leukemia cells, but by MTDAs only in THP-1 cells. 16761109 2006
Entrez Id: 10614
Gene Symbol: HEXIM1
HEXIM1 		0.010 Biomarker disease BEFREE His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia. 1682866 1991
Entrez Id: 7435
Gene Symbol: VIS1
VIS1 		0.010 Biomarker disease BEFREE His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia. 1682866 1991
Entrez Id: 3346
Gene Symbol: HTN1
HTN1 		0.010 Biomarker disease BEFREE His-1 and His-2: identification and chromosomal mapping of two commonly rearranged sites of viral integration in a myeloid leukemia. 1682866 1991
Entrez Id: 1440
Gene Symbol: CSF3
CSF3 		0.020 Biomarker disease BEFREE G-CSF is an effective growth factor for the blasts of myeloid leukemia. 1689609 1990
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.030 Biomarker disease BEFREE TNF plus protein synthesis inhibitor cycloheximide-induced apoptosis in human myelogenous leukemia ML-1a but not in C19, respiration minus mitochondrial DNA-deficient C19 cells, derived from ML-1a. 18468786 2008
Entrez Id: 3206
Gene Symbol: HOXA10
HOXA10 		0.010 AlteredExpression disease BEFREE HoxA10 is overexpressed in a poor prognosis subset of human acute myeloid leukemia (AML) and in vivo overexpression of HoxA10 in murine bone marrow induces myeloid leukemia. 21087928 2011
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.010 AlteredExpression disease BEFREE PTEN's regulation of VEGF and VEGFR1 expression and its clinical significance in myeloid leukemia. 21360018 2012
Entrez Id: 2624
Gene Symbol: GATA2
GATA2 		0.130 Biomarker disease BEFREE GATA-2 mediated regulation of normal hematopoietic stem/progenitor cell function, myelodysplasia and myeloid leukemia. 22192845 2012
Entrez Id: 3815
Gene Symbol: KIT
KIT 		0.060 GeneticVariation disease BEFREE KIT mutation detection in Tunisian patients with newly diagnosed myelogenous leukemia: prevalence and prognostic significance. 22939396 2012
Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1 		0.040 AlteredExpression disease BEFREE CD56 expression is an independent prognostic factor for relapse in acute myeloid leukemia with t(8;21). 23810283 2013
Entrez Id: 4684
Gene Symbol: NCAM1
NCAM1 		0.040 Biomarker disease BEFREE CD56 is recognized as an unfavorable prognostic marker in cases of acute myeloid leukemia with t(8;21), acute promyelocytic leukemia, and anaplastic large cell lymphoma. 24676459 2015