Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.330 Biomarker group BEFREE Osteopontin is an important mediator of alcoholic liver disease via hepatic stellate cell activation. 25278703 2014
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.330 GeneticVariation group BEFREE OPN gene polymorphisms were evaluated in patients with alcoholic liver disease. 23729174 2013
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.330 Biomarker group CTD_human Osteopontin (OPN) up-regulation is known to mediate hepatic inflammation in a rodent model of alcoholic liver disease (ALD) and alcohol ingestion is reported to inhibit hepatic peroxisome proliferator-activated receptor-alpha (PPAR-alpha) activity leading to hepatic steatosis and inflammation. 18703563 2008
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.330 AlteredExpression group BEFREE Osteopontin (OPN) up-regulation is known to mediate hepatic inflammation in a rodent model of alcoholic liver disease (ALD) and alcohol ingestion is reported to inhibit hepatic peroxisome proliferator-activated receptor-alpha (PPAR-alpha) activity leading to hepatic steatosis and inflammation. 18703563 2008