| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.370 | AlteredExpression | group | BEFREE | ATRA significantly increased the expression of Cx32 in the hepatoma tissues (P<0.01). | 26935255 | 2016 | ||||
|
0.370 | Biomarker | group | BEFREE | It may be expected to improve the cellular functions of the hepatoma cell line by Cx32 gene transfection and serve to develop an efficacious bioartificial liver. | 12849984 | 2003 | ||||
|
0.370 | Biomarker | group | BEFREE | Hepatocytes normally express Cx26 and Cx32 as their major gap junction genes, but HepG2 cells, a hepatoma cell line, are deficient in gap junctional intercellular communication (GJIC) based on the down-regulation of Cx26 and aberrant localization of Cx32. | 11576997 | 2001 | ||||
|
0.370 | GeneticVariation | group | BEFREE | Cx32 gene mutation in a chemically induced rat liver tumour. | 8824538 | 1996 | ||||
|
0.370 | GeneticVariation | group | BEFREE | Altered homologous and heterologous gap-junctional intercellular communication in primary human liver tumors associated with aberrant protein localization but not gene mutation of connexin 32. | 8262683 | 1994 | ||||
|
0.370 | Biomarker | group | BEFREE | To characterize the channel properties of the major rat liver gap junction protein (connexin 32) in isolation from other gap junction proteins, we have introduced the cDNA encoding it into a human hepatoma cell line (SKHep1) in which we have identified a gap junction deficiency. | 2154741 | 1990 | ||||
|
0.370 | AlteredExpression | group | BEFREE | These results are in striking contrast to the significant reductions in connexin 32 mRNA and protein expression observed in rat primary liver tumors induced by chemicals. | 2173931 | 1990 | ||||
|
0.370 | Biomarker | group | CTD_human | A rat liver gap junction (GJ) cDNA probe that detects mRNA encoding the 32 Kd GJ-protein (connexin 32) was employed to study GJ-protein gene expression in rat liver tumors induced by a single exposure to diethylnitrosamine (DEN) followed by exposure to 2-acetylaminofluorene (AAF)/CCl4/AAF or induced by systemic administration of N-ethyl-N-hydroxyethylnitrosamine (EHEN). | 2559087 | 1989 |