×
Entrez Id: 790
Gene Symbol: CAD
CAD
0.200
Biomarker
phenotype
RGD
Carbamyl phosphate-aspartate transcarbamylase activity in tumors.
13618893 1959
×
Entrez Id: 5471
Gene Symbol: PPAT
PPAT
0.300
Biomarker
phenotype
CTD_human
Purification, properties, and immunotitration of hepatoma glutamine phosphoribosylpyrophosphate amidotransferase (amidophosphoribosyltransferase, EC 2.4.2.14).
761203 1979
×
Entrez Id: 8540
Gene Symbol: AGPS
AGPS
0.200
Biomarker
phenotype
RGD
Activities of enzymes involved in the metabolism of ether-linked lipids in normal and neoplastic tissues of rat.
7407223 1980
×
Entrez Id: 1841
Gene Symbol: DTYMK
DTYMK
0.200
Biomarker
phenotype
RGD
Activities of some enzymes of pyrimidine and DNA synthesis in a rat transplantable hepatoma and human primary hepatomas, in cell lines derived from these tissues, and in human fetal liver.
6244089 1980
×
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
0.200
Biomarker
phenotype
RGD
Effects of hepatocarcinogens and hepatocarcinogenesis on the activity of rat liver microsomal epoxide hydrolase and observations on the electrophoretic behavior of this enzyme.
7260898 1981
×
Entrez Id: 1723
Gene Symbol: DHODH
DHODH
0.200
Biomarker
phenotype
RGD
Cyclic modulation of enzymes of pyrimidine nucleotide biosynthesis precedes sialoglycoconjugate changes during 2-acetylaminofluorene-induced hepatocarcinogenesis in the rat.
6331524 1984
×
Entrez Id: 158
Gene Symbol: ADSL
ADSL
0.200
Biomarker
phenotype
RGD
A comparison of succinyladenylate lyase activity and serum sialic acid as markers of malignancy.
2937404 1985
×
Entrez Id: 7498
Gene Symbol: XDH
XDH
0.200
Biomarker
phenotype
RGD
Decreased concentration of xanthine dehydrogenase (EC 1.1.1.204) in rat hepatomas.
3460692 1986
×
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
0.500
Biomarker
phenotype
CTD_human
Long-term dosing studies using mutagenic carcinogens indicate a highly significant correlation between elevations in the level of rat glutathione S-transferase P messenger RNA and liver tumours of hepatocellular origin.
3124819 1988
×
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.500
Biomarker
phenotype
RGD
Increased expression of the N-myc gene during normal and neoplastic rat liver growth.
3335218 1988
×
Entrez Id: 1373
Gene Symbol: CPS1
CPS1
0.200
ModifyingMutation
phenotype
RGD
Cloning of cDNA coding for carbamyl phosphate synthetase I and changes in levels of CPS1 mRNA during hepatocarcinogenesis.
3387993 1988
×
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
0.500
Biomarker
phenotype
CTD_human
Regulation of the expression of some genes for enzymes of glutathione metabolism in hepatotoxicity and hepatocarcinogenesis.
2563599 1989
×
Entrez Id: 2026
Gene Symbol: ENO2
ENO2
0.300
Biomarker
phenotype
CTD_human
Neuroendocrine dysdifferentiation and bombesin production in carcinogen-induced hepatocellular rat tumours.
2910524 1989
×
Entrez Id: 2922
Gene Symbol: GRP
GRP
0.300
Biomarker
phenotype
CTD_human
Neuroendocrine dysdifferentiation and bombesin production in carcinogen-induced hepatocellular rat tumours.
2910524 1989
×
Entrez Id: 5515
Gene Symbol: PPP2CA
PPP2CA
0.200
Biomarker
phenotype
RGD
Role of protein phosphatases in malignant transformation.
2562181 1989
×
Entrez Id: 2705
Gene Symbol: GJB1
GJB1
0.500
Biomarker
phenotype
RGD
Differential changes in expression of gap junction proteins connexin 26 and 32 during hepatocarcinogenesis in rats.
1336494 1992
×
Entrez Id: 2706
Gene Symbol: GJB2
GJB2
0.200
Biomarker
phenotype
RGD
Differential changes in expression of gap junction proteins connexin 26 and 32 during hepatocarcinogenesis in rats.
1336494 1992
×
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.300
Biomarker
phenotype
CTD_human
ras proto-oncogene activation in dichloroacetic acid-, trichloroethylene- and tetrachloroethylene-induced liver tumors in B6C3F1 mice.
7955063 1994
×
Entrez Id: 10400
Gene Symbol: PEMT
PEMT
0.200
Biomarker
phenotype
RGD
Suppression of rat hepatoma cell growth by expression of phosphatidylethanolamine N-methyltransferase-2.
7929120 1994
×
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
0.500
Biomarker
phenotype
CTD_human
Suppression of rat glutathione transferase P expression by peroxisome proliferators: interaction between Jun and peroxisome proliferator-activated receptor alpha.
7585603 1995
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.300
Biomarker
phenotype
CTD_human
Dehydroepiandrosterone is a complete hepatocarcinogen and potent tumor promoter in the absence of peroxisome proliferation in rainbow trout.
8603461 1995
×
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.200
Biomarker
phenotype
RGD
Low expression of the WAF1/CIP1 gene product, p21, in enzyme-altered foci induced in rat liver by diethylnitrosamine or phenobarbital.
8640740 1996
×
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.500
Biomarker
phenotype
CTD_human
Hepatic tumor induction in c-myc mono-transgenic and TGF-alpha/c-myc double-transgenic mice.
9079223 1997
×
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.500
Biomarker
phenotype
CTD_human
Hepatic tumor induction in c-myc mono-transgenic and TGF-alpha/c-myc double-transgenic mice.
9079223 1997
×
Entrez Id: 3482
Gene Symbol: IGF2R
IGF2R
0.200
Biomarker
phenotype
RGD
Imprinted M6p/Igf2 receptor is mutated in rat liver tumors.
9652747 1998