Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 834
Gene Symbol: CASP1
CASP1
0.010 Biomarker phenotype BEFREE The NLRP3/caspase-1/IL-1β axis is active in cartilaginous endplates of patients with Modic changes and inflammatory cascades can exacerbate the cartilaginous endplate degeneration which may act as a trigger for intervertebral disc degeneration and low back pain. 27146654 2016