Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | group | BEFREE | Our findings suggest that the MBL2 and ADRB2 genes exerts an important genetic influence on the lung disease in our patients. | 29703608 | 2018 | ||||
|
0.090 | Biomarker | group | BEFREE | The role of the MBL2 gene in lung disease severity in CF patients represents a very complex phenomenon where both genetic and environmental factors play an important role in addition to that of the MBL2 gene. | 22131319 | 2011 | ||||
|
0.090 | Biomarker | group | BEFREE | The available evidence therefore suggests that MBL insufficiency is associated with the severity of CF lung disease. | 21045008 | 2011 | ||||
|
0.090 | Biomarker | group | LHGDN | These findings provide evidence of gene-gene interaction in the pathogenesis of CF lung disease, whereby high TGF-beta1 production enhances the modulatory effect of MBL2 on the age of first bacterial infection and the rate of decline of pulmonary function. | 18292811 | 2008 | ||||
|
0.090 | GeneticVariation | group | LHGDN | Mannose-binding lectin polymorphisms and pulmonary outcome in premature neonates: a pilot study. | 17653692 | 2007 | ||||
|
0.090 | Biomarker | group | BEFREE | Mannan-binding lectin (MBL) deficiency has been reported to be associated with poor outcome in CF lung disease. | 15654829 | 2005 | ||||
|
0.090 | Biomarker | group | BEFREE | We, therefore, decided to treat a patient with CF, mannose-binding lectin deficiency, severe bronchopulmonary Pseudomonas aeruginosa infection, and rapid deterioration of lung function with purified mannose-binding lectin in an attempt to ameliorate the course of the lung disease. | 11836800 | 2002 | ||||
|
0.090 | Biomarker | group | BEFREE | The role of MBL in human pulmonary disease is less well established, although accumulating evidence suggests that it is a modifier for lung disease in tuberculosis and cystic fibrosis. | 16263483 | 2001 | ||||
|
0.090 | GeneticVariation | group | BEFREE | Association of mannose-binding lectin gene heterogeneity with severity of lung disease and survival in cystic fibrosis. | 10449435 | 1999 |