Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.240 Biomarker disease BEFREE PAI-1 may be a potential biomarker candidate for COPD-specific and extra-pulmonary manifestations. 28356730 2017
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.240 GeneticVariation disease BEFREE Conclusion The SERPINE1 -675 polymorphism, but not SERPINE1 -844 polymorphism, was associated with susceptibility to COPD in a Chinese Han population. 27856929 2016
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.240 AlteredExpression disease BEFREE Chronic lung inflammation with elevated p53 and PAI-1 expression in AECs and increased susceptibility to and exacerbation of respiratory infections are all associated with chronic obstructive pulmonary disease (COPD). 26747783 2016
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.240 Biomarker disease BEFREE We found increased p53, PAI-1 and apoptosis in AECs, with accumulation of macrophages and neutrophils in the lungs of patients with COPD. 25932922 2015
Entrez Id: 5054
Gene Symbol: SERPINE1
SERPINE1
0.240 Biomarker disease RGD [Effect of amiloride on the pathology of a rat model of chronic obstructive pulmonary disease]. 17651644 2007