Gene: H3P28 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 115482699
Gene Symbol: H3P28
H3P28 		0.040 Biomarker disease BEFREE Autoantibodies reacting with LINE-1 p40 characterize a population of SLE patients with severe and active disease. 31342656 2020
Entrez Id: 115482699
Gene Symbol: H3P28
H3P28 		0.040 Biomarker disease BEFREE Ustekinumab, a fully human IgG1κ monoclonal antibody directed towards the p40 shared subunit of IL-12 and IL-23, has been recently investigated in SLE, suggesting a potential novel therapeutic strategy in SLE. 30664357 2019
Entrez Id: 115482699
Gene Symbol: H3P28
H3P28 		0.040 AlteredExpression disease BEFREE In this experimental setting, we also demonstrated that IL-10-containing SLE PBMC supernatants inhibited IL-12 p35 and IL-12 p40 gene expression. 11014347 2000
Entrez Id: 115482699
Gene Symbol: H3P28
H3P28 		0.040 AlteredExpression disease BEFREE Downregulation of IL-12 p40 expression appears to be the cause of IL12 p70 deficiency in SLE. 10525320 1999