|
HLA-DRB1
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
This is the first large scale Korean study to genotype the HLA-DRB1 and -DPB1 alleles and to examine their association with myositis and MSAs.
|
30952422 |
2019 |
|
HLA-DRB1
|
0.080 |
Biomarker
|
disease |
BEFREE |
Association of Anti-3-Hydroxy-3-Methylglutaryl-Coenzyme A Reductase Autoantibodies With DRB1*07:01 and Severe Myositis in Juvenile Myositis Patients.
|
28129483 |
2017 |
|
HLA-DRB1
|
0.080 |
Biomarker
|
disease |
BEFREE |
HLA DRB1*04 was found in 4 of the 6 patients with thyroid disease and inflammatory myopathy.
|
17873759 |
2007 |
|
HLA-DRB1
|
0.080 |
Biomarker
|
disease |
BEFREE |
We detected novel HLA risk factors in African American patients with myositis overlap (DRB1*08) and in African American patients producing anti-signal recognition particle (DQA1*0102) and anti-Mi-2 autoantibodies (DRB1*0302).
|
17075818 |
2006 |
|
HLA-DRB1
|
0.080 |
Biomarker
|
disease |
BEFREE |
We have performed low to high resolution molecular typing to assess the genetic variability of major histocompatibility complex loci (HLA-A, -B, -Cw, -DRB1, and -DQA1) in a large population of European American patients with IIM (n = 571) representing the major myositis autoantibody groups.
|
16609350 |
2006 |
|
HLA-DRB1
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
HLA-DRB1 and TNF promoter genotypes were determined, and serum antinuclear autoantibodies were identified in 120 adult Japanese patients with IIM [72 with dermatomyositis (DM), 30 with polymyositis (PM), 18 with myositis overlapping with other collagen vascular diseases], as well as in 265 controls.
|
15338498 |
2004 |
|
HLA-DRB1
|
0.080 |
GeneticVariation
|
disease |
LHGDN |
HLA-DRB1 and TNF promoter genotypes were determined, and serum antinuclear autoantibodies were identified in 120 adult Japanese patients with IIM [72 with dermatomyositis (DM), 30 with polymyositis (PM), 18 with myositis overlapping with other collagen vascular diseases], as well as in 265 controls.
|
15338498 |
2004 |
|
HLA-DRB1
|
0.080 |
Biomarker
|
disease |
BEFREE |
However, DRB1*14 was a protective factor in Korean patients without myositis-specific autoantibodies (Pcorr = 0.004, OR 0.046).
|
10366124 |
1999 |
|
HLA-DRB1
|
0.080 |
GeneticVariation
|
disease |
BEFREE |
In addition, there appeared to be a negative association of the HLA-DR2 alleles (DRB1*1501 and *1503) with PM (P = 0.007, Pcorr not significant, OR = 0.39), but not with DM or myositis overall.
|
8814062 |
1996 |