Gene: CDKN2A ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 Biomarker group BEFREE Hereditary pancreatic carcinoma shows extant phenotypic and genotypic heterogeneity as evidenced by its integral association with a variety of hereditary cancer syndromes inclusive of the familial atypical multiple mole melanoma (FAMMM) syndrome in concert with CDKN2A (p16) germline mutations. 11815963 2002
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR Mutations associated with familial melanoma impair p16INK4 function. 7647780 1995
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR Inherited coding variants at the CDKN2A locus influence susceptibility to acute lymphoblastic leukaemia in children. 26104880 2015
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR Haplotype analysis and age estimation of the 113insR CDKN2A founder mutation in Swedish melanoma families. 11319798 2001
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR The M53I mutation in CDKN2A is a founder mutation that predominates in melanoma patients with Scottish ancestry. 17171691 2007
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL. 17047042 2006
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR Analysis of the CDKN2A, CDKN2B and CDK4 genes in 48 Australian melanoma kindreds. 9416844 1997
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR CDKN2A mutations and melanoma risk in the Icelandic population. 18178632 2008
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR Genotype analysis in Hungarian patients with multiple primary melanoma. 24660985 2014
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR CDKN2A germline mutations in individuals with cutaneous malignant melanoma. 17218939 2007
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR Analysis of the p16 gene, CDKN2, in 17 Australian melanoma kindreds. 8570179 1995
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR Homozygotes for CDKN2 (p16) germline mutation in Dutch familial melanoma kindreds. 7670475 1995
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR Protective effect of copy number polymorphism of glutathione S-transferase T1 gene on melanoma risk in presence of CDKN2A mutations, MC1R variants and host-related phenotypes. 19484507 2009
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR Increased prevalence of lung, breast, and pancreatic cancers in addition to melanoma risk in families bearing the cyclin-dependent kinase inhibitor 2A mutation: implications for genetic counseling. 25064638 2014
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR CDKN2A germline splicing mutation affecting both p16(ink4) and p14(arf) RNA processing in a melanoma/neurofibroma kindred. 11433531 2001
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR CDKN2A (p16INK4A) somatic and germline mutations. 8723678 1996
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR CDKN2A (P16(INK4a)) and CDK4 mutation analysis in 131 Australian melanoma probands: effect of family history and multiple primary melanomas. 10398427 1999
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR CDKN2A mutations in melanoma families from Uruguay. 19523171 2009
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families. 10922411 2000
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma. 9916806 1999
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR Hereditary p16-Leiden mutation in a patient with multiple head and neck tumors. 12549483 2003
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR Multiple neurofibromas as the presenting feature of familial atypical multiple malignant melanoma (FAMMM) syndrome. 23613284 2013
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR The p16INK4a/CDKN2A tumor suppressor and its relatives. 9823374 1998
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 CausalMutation group CLINVAR Temperature-sensitive mutants of p16CDKN2 associated with familial melanoma. 8668202 1996
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.110 GeneticVariation group CLINVAR Functional, structural, and genetic evaluation of 20 CDKN2A germ line mutations identified in melanoma-prone families or patients. 19260062 2009