Gene: MSH6 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Mutations of GTBP in genetically unstable cells. 7604266 1995
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Dominant negative mutator mutations in the mutS gene of Escherichia coli. 8071216 1994
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred. 9307272 1997
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Germline mutations in a polycytosine repeat of the hMSH6 gene in Korean hereditary nonpolyposis colorectal cancer. 9929971 1999
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR hMLH1, hMSH2 and hMSH6 mutations in hereditary non-polyposis colorectal cancer families from southern Sweden. 10471527 1999
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Familial endometrial cancer in female carriers of MSH6 germline mutations. 10508506 1999
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations. 10521294 1999
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Germ-line msh6 mutations in colorectal cancer families. 10537275 1999
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Mismatch recognition and DNA-dependent stimulation of the ATPase activity of hMutSalpha is abolished by a single mutation in the hMSH6 subunit. 10938287 2000
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR p53, CHK2, and CHK1 genes in Finnish families with Li-Fraumeni syndrome: further evidence of CHK2 in inherited cancer predisposition. 11479205 2001
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant. 11709755 2002
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation. 11807791 2002
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Involvement of hMSH6 in the development of hereditary and sporadic colorectal cancer revealed by immunostaining is based on germline mutations, but rarely on somatic inactivation. 11807791 2002
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach. 12373605 2002
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Ovarian cancer of endometrioid type as part of the MSH6gene mutation phenotype. 12376742 2002
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Conventional and tissue microarray immunohistochemical expression analysis of mismatch repair in hereditary colorectal tumors. 12547705 2003
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers. 12732731 2003
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Prevalence of defective DNA mismatch repair and MSH6 mutation in an unselected series of endometrial cancers. 12732731 2003
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR MSH6 germline mutations are rare in colorectal cancer families. 14520694 2003
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Mutation analysis of the MLH1, MSH2 and MSH6 genes in patients with double primary cancers of the colorectum and the endometrium: a population-based study in northern Sweden. 14961575 2004
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue. 14974087 2004
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Eight novel MSH6 germline mutations in patients with familial and nonfamilial colorectal cancer selected by loss of protein expression in tumor tissue. 14974087 2004
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Penetrance and expressivity of MSH6 germline mutations in seven kindreds not ascertained by family history. 15098177 2004
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR HNPCC: six new pathogenic mutations. 15217520 2004
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance. 15236168 2004