Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR "Familial associations in medullary thyroid carcinoma with Hirschsprung disease: the role of the RET-C620 ""Janus"" genetic variation." 20152359 2010
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 Biomarker group BEFREE RET is also the predisposition gene for the inherited cancer syndrome MEN 2A. 7716719 1995
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Actionable exomic incidental findings in 6503 participants: challenges of variant classification. 25637381 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma. 21765987 2011
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR RET revisited: expanding the oncogenic portfolio. 24561444 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Patients with RET D631Y mutations most commonly present with pheochromocytoma and not medullary thyroid carcinoma. 22274720 2012
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR A newly identified missense mutation in RET codon 666 is associated with the development of medullary thyroid carcinoma. 25319874 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Case report: a p.C618S RET proto-oncogene germline mutation in a large Chinese pedigree with familial medullary thyroid carcinoma. 22068382 2012
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Molecular diagnosis and comprehensive treatment of multiple endocrine neoplasia type 2 in Southeastern Chinese. 25628771 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Patient affected by neurofibromatosis type 1 and thyroid C-cell hyperplasia harboring pathogenic germ-line mutations in both NF1 and RET genes. 24361808 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Multiple endocrine neoplasia type 2: evaluation of the genotype-phenotype relationship. 12686527 2003
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Prevalence of germline mutations in patients with pheochromocytoma or abdominal paraganglioma and sporadic presentation: a population-based study in Western Sweden. 22270996 2012
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Skewed mutational spectrum of RET proto-oncogene Exon10 in Iranian patients with medullary thyroid carcinoma. 25694125 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR The clinical spectrum of RET proto-oncogene mutations in codon 790. 23756355 2013
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR The rare intracellular RET mutation p.S891A in a Chinese Han family with familial medullary thyroid carcinoma. 24845513 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR A new hot spot for mutations in the ret protooncogene causing familial medullary thyroid carcinoma and multiple endocrine neoplasia type 2A. 9506724 1998
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Hirschsprung disease in MEN 2A: increased spectrum of RET exon 10 genotypes and strong genotype-phenotype correlation. 9384613 1998
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC. 7907913 1994
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 AlteredExpression group BEFREE Germ-line mutations, mainly point mutations, that lead to constitutive activation of RET tyrosine kinase activity are responsible for the development of the inherited cancer syndrome, multiple endocrine neoplasia type 2. 11114739 2000
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Various penetrance of familial medullary thyroid carcinoma in patients with RET protooncogene codon 790/791 germline mutations. 12409662 2002
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Genetic testing in medullary thyroid carcinoma syndromes: mutation types and clinical significance. 9146685 1997
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Coexistence of multiple endocrine neoplasia type 1 and type 2 in a large Italian family. 21678021 2011
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR How to Assess the Clinical Relevance of Novel RET Missense Variants in the Absence of Functional Studies? 27099842 2016
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Genotype-specific progression of hereditary medullary thyroid cancer. 29656518 2018
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Protecting thyroid cancer patients from untoward effects of radioactive iodine treatment. 19731974 2009