Gene: MSH6 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes. 28944238 2017
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR A cohort analysis of men with a family history of BRCA1/2 and Lynch mutations for prostate cancer. 27456091 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Multigene Panel Testing Provides a New Perspective on Lynch Syndrome. 28514183 2017
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR A massive parallel sequencing workflow for diagnostic genetic testing of mismatch repair genes. 24689082 2014
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR CoDP: predicting the impact of unclassified genetic variants in MSH6 by the combination of different properties of the protein. 23621914 2013
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Characterization of a novel founder MSH6 mutation causing Lynch syndrome in the French Canadian population. 25318681 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Germline mutations of the hMLH1 and hMSH2 mismatch repair genes in Belgian hereditary nonpolyposis colon cancer (HNPCC) patients. 16736289 2006
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR A multifactorial likelihood model for MMR gene variant classification incorporating probabilities based on sequence bioinformatics and tumor characteristics: a report from the Colon Cancer Family Registry. 22949379 2013
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Comprehensive population-wide analysis of Lynch syndrome in Iceland reveals founder mutations in MSH6 and PMS2. 28466842 2017
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Inherited Mutations in Women With Ovarian Carcinoma. 26720728 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Screening for Lynch syndrome (hereditary nonpolyposis colorectal cancer) among endometrial cancer patients. 16885385 2006
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Longitudinal analysis of treatment-induced genomic alterations in gliomas. 28153049 2017
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants. 22102614 2012
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Massively Parallel Sequencing-Based Clonality Analysis of Synchronous Endometrioid Endometrial and Ovarian Carcinomas. 26832770 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer. 17453009 2007
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. 23263490 2013
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR MSH6 mutation in Muir-Torre syndrome: could this be a rare finding? 17199584 2007
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Combined iPLEX and TaqMan assays to screen for 45 common mutations in Lynch syndrome and FAP patients. 20007843 2010
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR High frequency of exon deletions and putative founder effects in French Canadian Lynch syndrome families. 19459153 2009
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 GeneticVariation group CLINVAR Classification of mismatch repair gene missense variants with PON-MMR. 22290698 2012
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Identification of germline genetic mutations in patients with pancreatic cancer. 26440929 2015
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Integrative analysis of hereditary nonpolyposis colorectal cancer: the contribution of allele-specific expression and other assays to diagnostic algorithms. 24278394 2013
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR Compound heterozygosity for two MSH6 mutations in a patient with early onset of HNPCC-associated cancers, but without hematological malignancy and brain tumor. 16418736 2006
Entrez Id: 2956
Gene Symbol: MSH6
MSH6 		0.110 CausalMutation group CLINVAR The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population. 24728189 2014