Gene: CDH1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 GeneticVariation group BEFREE The E-cadherin gene (CDH1) is frequently mutated in diffuse gastric cancer and lobular breast cancer, and germline mutations predispose to the cancer syndrome Hereditary Diffuse Gastric Cancer. 30066183 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 GeneticVariation group BEFREE In addition, germline mutations in CDH1 predispose to the autosomal dominant cancer syndrome Hereditary Diffuse Gastric Cancer (HDGC). 31467357 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR A Life Potentially Saved Through Hereditary Cancer Panel Testing. 28195815 2017
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Next-generation sequencing in familial breast cancer patients from Lebanon. 28202063 2017
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Prophylactic Total Gastrectomy: a Prospective Cohort Study of Long-Term Impact on Quality of Life. 27752808 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Roles for E-cadherin cell surface regulation in cancer. 27582386 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Panel testing reveals nonsense and missense CDH1 mutations in families without hereditary diffuse gastric cancer. 27064202 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Prophylactic total gastrectomy in the management of hereditary tumor syndromes. 27682646 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Chromoendoscopy in combination with random biopsies does not improve detection of gastric cancer foci in CDH1 mutation positive patients. 27995193 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. 26182300 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment. 26270727 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. 25525159 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Accuracy of Hereditary Diffuse Gastric Cancer Testing Criteria and Outcomes in Patients With a Germline Mutation in CDH1. 26072394 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Tumor genome analysis includes germline genome: are we ready for surprises? 25123297 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers. 25979631 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Hereditary diffuse gastric cancer syndrome: improved performances of the 2015 testing criteria for the identification of probands with a CDH1 germline mutation. 26025002 2015
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer. 25315765 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Germline CDH1 mutations in bilateral lobular carcinoma in situ. 24366306 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Rescue of wild-type E-cadherin expression from nonsense-mutated cancer cells by a suppressor-tRNA. 24424122 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Prophylactic total gastrectomy in hereditary diffuse gastric cancer: identification of two novel CDH1 gene mutations-a clinical observational study. 24389957 2014
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 GeneticVariation group CLINVAR CDH1 germline mutations and the hereditary diffuse gastric and lobular breast cancer syndrome: a multicentre study. 23709761 2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Hereditary diffuse gastric cancer: a family diagnosis and treatment. 22723466 2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 CausalMutation group CLINVAR Laparoscopic prophylactic total gastrectomy with linear stapler side-to-side esophagojejunal anastomosis for hereditary diffuse gastric cancer syndrome in 2 siblings. 23752020 2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1 		0.130 GeneticVariation group CLINVAR The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC. 22850631 2013