| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | group | BEFREE | Their connectivity map included interleukin-6 (IL-6) and tumour necrosis factor α (TNF-α) as central nodes and the pathway identified with the highest score was involved in neurological disease, psychological disorders, and cellular movement. | 29301248 | 2018 | ||||
|
0.070 | Biomarker | group | BEFREE | Further research is required to determine how CNS inflammatory changes associated with IL-6, IL-10 and IL-6R could in turn contribute to the development of CNS neurological disorders. | 28456715 | 2017 | ||||
|
0.070 | AlteredExpression | group | BEFREE | We retrospectively investigated the IL-6 levels of 572 consecutive CSF samples in patients with various neurological disorders. | 28283439 | 2017 | ||||
|
0.070 | AlteredExpression | group | BEFREE | IL-6 is also expressed chronically at elevated levels in the central nervous system (CNS) under pathological conditions such as neurological disorders. | 29104031 | 2017 | ||||
|
0.070 | GeneticVariation | group | BEFREE | An autoinflammatory neurological disease due to interleukin 6 hypersecretion. | 23432807 | 2013 | ||||
|
0.070 | Biomarker | group | BEFREE | In order to evaluate the role of NO and IL-6 in neurological disorders such as seizures, we investigated 19 adults with intellectual disability (ID) who suffer from epilepsy and treated for convulsions. | 18834707 | 2009 | ||||
|
0.070 | Biomarker | group | BEFREE | ATP-binding cassette transporters A1 and C6, peroxisome proliferator activated receptor alpha, interleukin-6); and (3) studies showing that multiple genes appear to be at the intersection of several age-related disorders such as cardiovascular disease, neurological disorders and osteoporosis (i.e. apolipoprotein E, vitamin D receptor, matrix Gla protein, peroxisome proliferator activated receptor gamma, angiotensin-converting enzyme, estrogen receptor, androgen receptor, methylenetetrahydrofolate reductase). | 12544661 | 2003 |