×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
GeneticVariation
disease
BEFREE
A mutation of carboxypeptidase E (CPE ), an enzyme active in the processing and sorting of prohormones, causes obesity in the fat/fat mouse.
9207799
1997
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
MGD
Atherosclerosis in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow.
8177043
1994
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
CTD_human
Augmented pulmonary responses to acute ozone exposure in obese mice: roles of TNFR2 and IL-13.
23434795
2013
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
MGD
Carboxypeptidase E (CPE) deficiency in mice with the fat mutation have reduced stomach function.
9893169
1999
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
MGD
Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice.
9019408
1997
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
MGD
Characterization of plasma lipids in genetically obese mice: the mutants obese, diabetes, fat, tubby, and lethal yellow.
8177042
1994
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
MGD
Deficiencies in pro-thyrotropin-releasing hormone processing and abnormalities in thermoregulation in Cpefat/fat mice.
12270926
2002
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
MGD
Fat (fat) and tubby (tub): two autosomal recessive mutations causing obesity syndromes in the mouse.
2250094
1991
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
MGD
Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity.
7663508
1995
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
MGD
Intracellular misrouting and abnormal secretion of adrenocorticotropin and growth hormone in cpefat mice associated with a carboxypeptidase E mutation.
9144234
1997
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
GENOMICS_ENGLAND
The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits.
15358678
2004
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
CTD_human
The carboxypeptidase E knockout mouse exhibits endocrinological and behavioral deficits.
15358678
2004
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
Biomarker
disease
BEFREE
The involvement of CPE and THBS1 in obesity allows us to suggest that the physiological processes controlled by these genes contribute to depot and gender-related differences in the metabolic complications of obesity .
12530526
2002
×
Entrez Id:
1363
Gene Symbol:
CPE
CPE
0.730
GeneticVariation
disease
BEFREE
Thus, genetic variation in the CPE gene does not appear to play a major role in the pathogenesis of NIDDM or obesity in Japanese subjects.
9662053
1998