Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | We conducted a case-control study to analyze he relationship of VDR gene polymorphisms with the occurrence and prognosis of osteosarcoma. | 30568875 | 2019 | ||||
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0.080 | AlteredExpression | disease | BEFREE | In the current study, human osteosarcoma Saos-2 cells and primary human osteoblasts were found to express mRNA for the vitamin D receptor as well as activating and deactivating enzymes in vitamin D<sub>3</sub> metabolism. | 31352041 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | By employing reporter gene assay, polymerase chain reaction, and western blotting, we monitored the VDR activity and expression in cell cultures of intestinal (LS180), osteosarcoma (HOS), and normal human osteoblasts in vitro. | 31471674 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The results show that the expression of vitamin D receptor in osteosarcoma cell line SAOS-2 is significantly down-modulated by exposure to aflatoxin B1. | 25483621 | 2015 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The synthesized 16-ene-2α-methyl-1α,15α,25-trihydroxyvitamin D(3) showed almost 3-times higher VDR binding affinity and an equipotent level of osteocalcin promoter transactivation activity in human osteosarcoma cells as compared to 1α,25(OH)(2)D(3). | 22213321 | 2012 | ||||
|
0.080 | AlteredExpression | disease | LHGDN | Overexpression of VDR in MG-63 osteosarcoma cells induced the expression of HRH1 and DPT. | 17547532 | 2007 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Functional interference between AP-1 and the vitamin D receptor on osteocalcin gene expression in human osteosarcoma cells. | 8076631 | 1994 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Homologous and heterologous regulation of 1,25-dihydroxyvitamin D-3 receptor mRNA levels in human osteosarcoma cells. | 1846564 | 1991 |