Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.370 Biomarker disease BEFREE Moreover, 17 hub nodes of WMP (PTGS2, BCL2, TP53, IL6, MAPK1, EGFR, EGF, CASP3, JUN, MAPK8, MMP9, VEGFA, TNF, MYC, AKT1, FOS and TGFB1) were recognized as potential targets of treatments, implying the underlying mechanisms of WMP acting on pancreatic neoplasms. 31272505 2019
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.370 GeneticVariation disease BEFREE Deletion of Lfng resulted in downregulation of Tgfb1, Tgfb2 and Tgfbr2 expression in the wild-type pancreas at all ages examined, and in the Kras(LSL-G12D/+);Pdx1-Cre pancreas after PDAC onset, as well as reduced phospho-Smad2 levels in pancreatic tumors. 26279302 2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.370 Biomarker disease BEFREE Negative control of TRAIL-R1 signaling by transforming growth factor β1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1. 27492861 2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.370 Biomarker disease CTD_human Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-κB pathway. 23992306 2013
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.370 Biomarker disease BEFREE In the present study, SD-208, a 2,4-disubstituted pteridine, ATP-competitive inhibitor of the TGFbeta receptor I kinase (TGFbetaRI), was used to inhibit cellular activities and tumor progression of PANC-1, a human pancreatic tumor line. 17400764 2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.370 AlteredExpression disease LHGDN Serum transforming growth factor-beta1 levels and pancreatic cancer risk: a nested case-control study (Japan). 16933058 2006
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.370 AlteredExpression disease LHGDN A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis. 15184872 2004
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.370 Biomarker disease LHGDN Induction and expression of betaig-h3 in pancreatic cancer cells. 12379307 2002