×
Entrez Id:
7040
Gene Symbol:
TGFB1
TGFB1
0.370
Biomarker
disease
BEFREE
Moreover, 17 hub nodes of WMP (PTGS2, BCL2, TP53, IL6, MAPK1, EGFR, EGF, CASP3, JUN, MAPK8, MMP9, VEGFA, TNF, MYC, AKT1, FOS and TGFB1 ) were recognized as potential targets of treatments, implying the underlying mechanisms of WMP acting on pancreatic neoplasms .
31272505
2019
×
Entrez Id:
7040
Gene Symbol:
TGFB1
TGFB1
0.370
GeneticVariation
disease
BEFREE
Deletion of Lfng resulted in downregulation of Tgfb1 , Tgfb2 and Tgfbr2 expression in the wild-type pancreas at all ages examined, and in the Kras(LSL-G12D /+);Pdx1-Cre pancreas after PDAC onset, as well as reduced phospho-Smad2 levels in pancreatic tumors .
26279302
2016
×
Entrez Id:
7040
Gene Symbol:
TGFB1
TGFB1
0.370
Biomarker
disease
BEFREE
Negative control of TRAIL-R1 signaling by transforming growth factor β1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1.
27492861
2016
×
Entrez Id:
7040
Gene Symbol:
TGFB1
TGFB1
0.370
Biomarker
disease
CTD_human
Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-κB pathway.
23992306
2013
×
Entrez Id:
7040
Gene Symbol:
TGFB1
TGFB1
0.370
Biomarker
disease
BEFREE
In the present study, SD-208, a 2,4-disubstituted pteridine, ATP-competitive inhibitor of the TGFbeta receptor I kinase (TGFbetaRI), was used to inhibit cellular activities and tumor progression of PANC-1, a human pancreatic tumor line.
17400764
2007
×
Entrez Id:
7040
Gene Symbol:
TGFB1
TGFB1
0.370
AlteredExpression
disease
LHGDN
Serum transforming growth factor-beta1 levels and pancreatic cancer risk: a nested case-control study (Japan).
16933058
2006
×
Entrez Id:
7040
Gene Symbol:
TGFB1
TGFB1
0.370
AlteredExpression
disease
LHGDN
A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-beta in pancreatic carcinogenesis.
15184872
2004
×
Entrez Id:
7040
Gene Symbol:
TGFB1
TGFB1
0.370
Biomarker
disease
LHGDN
Induction and expression of betaig-h3 in pancreatic cancer cells.
12379307
2002