Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 374920
Gene Symbol: ZSWIM9
ZSWIM9
0.300 Biomarker disease CTD_human Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles. 21411543 2011
Entrez Id: 57829
Gene Symbol: ZP4
ZP4
0.010 AlteredExpression disease BEFREE Study on the zona pellucida 4 (ZP4) gene sequence and its expression in the ovaries of patients with polycystic ovary syndrome. 25740067 2015
Entrez Id: 10534
Gene Symbol: ZNRD2
ZNRD2
0.020 Biomarker disease BEFREE Our results also provide a mechanistic explanation for the functional link between hyperinsulinemia and p27 loss in the pathogenesis of endometrial epithelial hyperplasia in PCOS patients. 29112933 2018
Entrez Id: 10534
Gene Symbol: ZNRD2
ZNRD2
0.020 AlteredExpression disease BEFREE LINC-01572:28 and p27 protein were elevated whereas proliferating cell nuclear antigen protein was decreased in the hLGCs of women with PCOS. 30293818 2018
Entrez Id: 80264
Gene Symbol: ZNF430
ZNF430
0.300 Biomarker disease CTD_human Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles. 21411543 2011
Entrez Id: 57862
Gene Symbol: ZNF410
ZNF410
0.030 Biomarker disease BEFREE We undertook this study to investigate the association pattern of VDR polymorphisms (Cdx2, Fok1, Apa1 and Taq1) with PCOS among Indian women. 26458343 2015
Entrez Id: 57862
Gene Symbol: ZNF410
ZNF410
0.030 GeneticVariation disease BEFREE Haplotype Taq-I C/ Apa-I C was associated with a higher PCOS risk more than controls. 24078159 2013
Entrez Id: 57862
Gene Symbol: ZNF410
ZNF410
0.030 GeneticVariation disease BEFREE We investigated the genotype and haplotype distribution of the Bsm-I (rs1544410), Apa-I (rs7975232), and Taq-I (rs731236) VDR gene polymorphisms in PCOS and non-hirsute women from southern Brazil. 29669566 2018
Entrez Id: 7764
Gene Symbol: ZNF217
ZNF217
0.020 Biomarker disease BEFREE ZNF217 was decreased in the granulosa cells both of dehydroepiandrosterone-treated rats and of women with polycystic ovary syndrome. 31454071 2020
Entrez Id: 7764
Gene Symbol: ZNF217
ZNF217
0.020 Biomarker disease BEFREE Zinc finger gene 217 (ZNF217) is a candidate gene of polycystic ovary syndrome (PCOS) which is vulnerable to ovarian hyperstimulation syndrome (OHSS). 28607476 2017
Entrez Id: 7755
Gene Symbol: ZNF205
ZNF205
0.300 Biomarker disease CTD_human Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles. 21411543 2011
Entrez Id: 9205
Gene Symbol: ZMYM5
ZMYM5
0.300 Biomarker disease CTD_human Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles. 21411543 2011
Entrez Id: 100125288
Gene Symbol: ZGLP1
ZGLP1
0.030 AlteredExpression disease BEFREE GLP-1 levels were comparable in PCOS vs controls. 28432082 2017
Entrez Id: 100125288
Gene Symbol: ZGLP1
ZGLP1
0.030 GeneticVariation disease BEFREE Expert commentary: The available studies of GLP-1 RA therapy in the treatment of excess body weight in women with PCOS demonstrate that exenatide and liraglutide are effective in weight reduction either as monotherapy or in combination with metformin. 28276778 2017
Entrez Id: 100125288
Gene Symbol: ZGLP1
ZGLP1
0.030 Biomarker disease BEFREE Interventions like metformin, orlistat, hormonal contraceptives, GLP1 agonists, and VitD have been applied to ameliorate or reverse the pathological characterization of PCOS. 31029778 2019
Entrez Id: 7704
Gene Symbol: ZBTB16
ZBTB16
0.100 GeneticVariation disease GWASCAT Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations. 26284813 2015
Entrez Id: 7704
Gene Symbol: ZBTB16
ZBTB16
0.100 GeneticVariation disease GWASCAT Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria. 30566500 2018
Entrez Id: 7534
Gene Symbol: YWHAZ
YWHAZ
0.010 Biomarker disease BEFREE The most stable HKGs observed across both PCOS endometrium were found to be YWHAZ, CYC1 and ACTB. 22052386 2012
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
0.150 GeneticVariation disease GWASDB Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. 22885925 2012
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
0.150 GeneticVariation disease GWASCAT Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. 26416764 2015
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
0.150 Biomarker disease BEFREE We identify six signals for PCOS at genome-wide statistical significance (P<5 × 10(-8)), in/near genes ERBB4/HER4, YAP1, THADA, FSHB, RAD50 and KRR1. 26416764 2015
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
0.150 Biomarker disease BEFREE YAP1 appears to be a new susceptibility gene for PCOS in Han Chinese women. 22499345 2012
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
0.150 Biomarker disease BEFREE These findings not only elucidated the role of YAP1 in maintaining normal ovarian functions, but also link the YAP1 deregulation to the pathogenesis of PCOS. 28961951 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
0.150 PosttranslationalModification disease BEFREE Overall methylation level of YAP1 promoter region from PCOS group was significantly lower than that from control group. 28079802 2017
Entrez Id: 10413
Gene Symbol: YAP1
YAP1
0.150 GeneticVariation disease GWASCAT Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome. 22885925 2012