×
Entrez Id:
374920
Gene Symbol:
ZSWIM9
ZSWIM9
0.300
Biomarker
disease
CTD_human
Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.
21411543
2011
×
Entrez Id:
57829
Gene Symbol:
ZP4
ZP4
0.010
AlteredExpression
disease
BEFREE
Study on the zona pellucida 4 (ZP4 ) gene sequence and its expression in the ovaries of patients with polycystic ovary syndrome .
25740067
2015
×
Entrez Id:
10534
Gene Symbol:
ZNRD2
ZNRD2
0.020
Biomarker
disease
BEFREE
Our results also provide a mechanistic explanation for the functional link between hyperinsulinemia and p27 loss in the pathogenesis of endometrial epithelial hyperplasia in PCOS patients.
29112933
2018
×
Entrez Id:
10534
Gene Symbol:
ZNRD2
ZNRD2
0.020
AlteredExpression
disease
BEFREE
LINC-01572:28 and p27 protein were elevated whereas proliferating cell nuclear antigen protein was decreased in the hLGCs of women with PCOS .
30293818
2018
×
Entrez Id:
80264
Gene Symbol:
ZNF430
ZNF430
0.300
Biomarker
disease
CTD_human
Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.
21411543
2011
×
Entrez Id:
57862
Gene Symbol:
ZNF410
ZNF410
0.030
Biomarker
disease
BEFREE
We undertook this study to investigate the association pattern of VDR polymorphisms (Cdx2, Fok1, Apa1 and Taq1) with PCOS among Indian women.
26458343
2015
×
Entrez Id:
57862
Gene Symbol:
ZNF410
ZNF410
0.030
GeneticVariation
disease
BEFREE
Haplotype Taq-I C/ Apa-I C was associated with a higher PCOS risk more than controls.
24078159
2013
×
Entrez Id:
57862
Gene Symbol:
ZNF410
ZNF410
0.030
GeneticVariation
disease
BEFREE
We investigated the genotype and haplotype distribution of the Bsm-I (rs1544410 ), Apa-I (rs7975232 ), and Taq-I (rs731236 ) VDR gene polymorphisms in PCOS and non-hirsute women from southern Brazil.
29669566
2018
×
Entrez Id:
7764
Gene Symbol:
ZNF217
ZNF217
0.020
Biomarker
disease
BEFREE
ZNF217 was decreased in the granulosa cells both of dehydroepiandrosterone-treated rats and of women with polycystic ovary syndrome .
31454071
2020
×
Entrez Id:
7764
Gene Symbol:
ZNF217
ZNF217
0.020
Biomarker
disease
BEFREE
Zinc finger gene 217 (ZNF217 ) is a candidate gene of polycystic ovary syndrome (PCOS ) which is vulnerable to ovarian hyperstimulation syndrome (OHSS).
28607476
2017
×
Entrez Id:
7755
Gene Symbol:
ZNF205
ZNF205
0.300
Biomarker
disease
CTD_human
Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.
21411543
2011
×
Entrez Id:
9205
Gene Symbol:
ZMYM5
ZMYM5
0.300
Biomarker
disease
CTD_human
Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles.
21411543
2011
×
Entrez Id:
100125288
Gene Symbol:
ZGLP1
ZGLP1
0.030
AlteredExpression
disease
BEFREE
GLP-1 levels were comparable in PCOS vs controls.
28432082
2017
×
Entrez Id:
100125288
Gene Symbol:
ZGLP1
ZGLP1
0.030
GeneticVariation
disease
BEFREE
Expert commentary: The available studies of GLP-1 RA therapy in the treatment of excess body weight in women with PCOS demonstrate that exenatide and liraglutide are effective in weight reduction either as monotherapy or in combination with metformin.
28276778
2017
×
Entrez Id:
100125288
Gene Symbol:
ZGLP1
ZGLP1
0.030
Biomarker
disease
BEFREE
Interventions like metformin, orlistat, hormonal contraceptives, GLP1 agonists, and VitD have been applied to ameliorate or reverse the pathological characterization of PCOS .
31029778
2019
×
Entrez Id:
7704
Gene Symbol:
ZBTB16
ZBTB16
0.100
GeneticVariation
disease
GWASCAT
Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations.
26284813
2015
×
Entrez Id:
7704
Gene Symbol:
ZBTB16
ZBTB16
0.100
GeneticVariation
disease
GWASCAT
Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria.
30566500
2018
×
Entrez Id:
7534
Gene Symbol:
YWHAZ
YWHAZ
0.010
Biomarker
disease
BEFREE
The most stable HKGs observed across both PCOS endometrium were found to be YWHAZ , CYC1 and ACTB.
22052386
2012
×
Entrez Id:
10413
Gene Symbol:
YAP1
YAP1
0.150
GeneticVariation
disease
GWASDB
Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.
22885925
2012
×
Entrez Id:
10413
Gene Symbol:
YAP1
YAP1
0.150
GeneticVariation
disease
GWASCAT
Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome.
26416764
2015
×
Entrez Id:
10413
Gene Symbol:
YAP1
YAP1
0.150
Biomarker
disease
BEFREE
We identify six signals for PCOS at genome-wide statistical significance (P<5 × 10(-8)), in/near genes ERBB4/HER4, YAP1 , THADA, FSHB, RAD50 and KRR1.
26416764
2015
×
Entrez Id:
10413
Gene Symbol:
YAP1
YAP1
0.150
Biomarker
disease
BEFREE
YAP1 appears to be a new susceptibility gene for PCOS in Han Chinese women.
22499345
2012
×
Entrez Id:
10413
Gene Symbol:
YAP1
YAP1
0.150
Biomarker
disease
BEFREE
These findings not only elucidated the role of YAP1 in maintaining normal ovarian functions, but also link the YAP1 deregulation to the pathogenesis of PCOS .
28961951
2017
×
Entrez Id:
10413
Gene Symbol:
YAP1
YAP1
0.150
PosttranslationalModification
disease
BEFREE
Overall methylation level of YAP1 promoter region from PCOS group was significantly lower than that from control group.
28079802
2017
×
Entrez Id:
10413
Gene Symbol:
YAP1
YAP1
0.150
GeneticVariation
disease
GWASCAT
Genome-wide association study identifies eight new risk loci for polycystic ovary syndrome.
22885925
2012