Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.090 | Biomarker | disease | BEFREE | This article is part of a special issue entitled: PI3K-AKT-FOXO axis in psoriasis. | 30483877 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | Interestingly, some of the identified proteins and pathways with significantly different modifications, such as S100A9 and the PI3K-Akt signaling pathway, have been previously reported to be associated with psoriasis. | 31229693 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | PSORI-CM02 ameliorates psoriasis in vivo and in vitro by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway. | 31401494 | 2019 | ||||
|
0.090 | Biomarker | disease | BEFREE | PI3K/AKT/mTOR activation and autophagy inhibition plays a key role in increased cholesterol during IL-17A mediated inflammatory response in psoriasis. | 29432814 | 2018 | ||||
|
0.090 | Biomarker | disease | BEFREE | PI3K-Akt signaling pathway and five other pathways had close correlation with the pathogenesis of psoriasis and could deserve further research. | 29537306 | 2018 | ||||
|
0.090 | Biomarker | disease | BEFREE | We recently reported that the PI3K/Akt/mTOR pathway that is frequently deregulated in many malignancies is also clinically relevant for psoriasis. | 27393705 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | However, the expression of PTEN and the correlation between PTEN and PI3K/Akt have not been investigated in patients with psoriasis. | 24168180 | 2014 | ||||
|
0.090 | Biomarker | disease | BEFREE | This novel observation provides the scope to develop new therapeutics targeting PI3K/Akt/mTOR signaling pathway in autoimmune diseases like psoriasis and rheumatoid arthritis. | 22840496 | 2012 | ||||
|
0.090 | Biomarker | disease | BEFREE | Taken together, these data indicate that PI3Kδ and/or PI3Kγ inhibitors should be considered for treating IL-17-driven diseases, such as psoriasis. | 23024273 | 2012 |