Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4 		0.010 Biomarker disease BEFREE SMAD4 knockdown (KD) suppressed the production of these BMP inhibitors by SCZ GPCs and rescued normal astrocytic differentiation. 31242417 2019
Entrez Id: 5978
Gene Symbol: REST
REST 		0.010 AlteredExpression disease BEFREE REST KD also rescued potassium-transport-associated gene expression and K<sup>+</sup> uptake, which were otherwise deficient in SCZ glia. 31242417 2019
Entrez Id: 3655
Gene Symbol: ITGA6
ITGA6 		0.010 Biomarker disease BEFREE Among the genes found disrupted in our study, SEZ6, RYR2, GPR153, GTF2IRD1, TTBK1 and ITGA6 have been previously linked to neuronal function or to psychiatric disorders, and thus may be considered as COS candidate genes. 26508570 2016
Entrez Id: 3084
Gene Symbol: NRG1
NRG1 		0.010 Biomarker disease BEFREE By contrast, in healthy children, possession of the risk allele was associated with different trajectories in gray matter only and was confined to frontotemporal regions, reflecting epistatic or other illness-specific effects mediating NRG1 influence on brain development in COS. 17033632 2007
Entrez Id: 5740
Gene Symbol: PTGIS
PTGIS 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 5970
Gene Symbol: RELA
RELA 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 4232
Gene Symbol: MEST
MEST 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 342667
Gene Symbol: STAC2
STAC2 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 84630
Gene Symbol: TTBK1
TTBK1 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 339231
Gene Symbol: ARL16
ARL16 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 282809
Gene Symbol: POC1B
POC1B 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 8693
Gene Symbol: GALNT4
GALNT4 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 91662
Gene Symbol: NLRP12
NLRP12 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 124925
Gene Symbol: SEZ6
SEZ6 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 387509
Gene Symbol: GPR153
GPR153 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 341640
Gene Symbol: FREM2
FREM2 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 23024
Gene Symbol: PDZRN3
PDZRN3 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 9146
Gene Symbol: HGS
HGS 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 100528030
Gene Symbol: POC1B-GALNT4
POC1B-GALNT4 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 9569
Gene Symbol: GTF2IRD1
GTF2IRD1 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 192134
Gene Symbol: B3GNT6
B3GNT6 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 51268
Gene Symbol: PIPOX
PIPOX 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 3339
Gene Symbol: HSPG2
HSPG2 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 6262
Gene Symbol: RYR2
RYR2 		0.100 GeneticVariation disease CLINVAR De novo variants in sporadic cases of childhood onset schizophrenia. 26508570 2016
Entrez Id: 2571
Gene Symbol: GAD1
GAD1 		0.020 Biomarker disease BEFREE In the present study, SNPs in and around the GAD1 gene, which encodes the protein GAD67, were tested on a rare, severely ill group of children and adolescents with childhood-onset schizophrenia (COS) (n=72), in a family-based association analysis. 15505639 2005