| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | Our data suggest that the TNFSF13B functional variant does not contribute to the genetic network underlying GCA and SSc. | 30586461 | 2018 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In addition, serum B cell activating factor (BAFF) level is correlated with SSc severity and activity. | 30009261 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Sera from pSS patients enrolled in the UK Primary Sjögren's Syndrome Registry (UKPSSR) (n = 553) and healthy controls (n = 286) were analysed for FLC (κ and λ), BAFF and β2 M. Pearson correlation coefficients were calculated for patient clinical characteristics, including salivary flow, Schirmer's test, EULAR Sjögren's Syndrome Patient Reported Index and serum IgG levels. | 29608774 | 2018 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The presence of IFN type I signature in monocytes is correlated with BAFF mRNA expression and serum PIIINP levels, supporting a contribution in the pathogenesis and progression of SSc. | 26371289 | 2016 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Our data suggest a critical role of miR-30a-3p in the regulation of BAFF expression, which could have a major impact in the regulation of the autoimmune responses occurring in RA and SSc. | 25360821 | 2014 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Cocultures of blood B cells from healthy blood donors and normal or SSc dermal fibroblasts stimulated with anti-IgM and BAFF were performed. | 24289101 | 2013 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | To investigate the association between haplotypes in the 5' regulatory region of the B-lymphocyte activating factor (BAFF) gene, disease susceptibility and serum BAFF (s-BAFF) levels in Caucasian primary SS (pSS) patients. | 18617551 | 2008 | ||||
|
0.080 | AlteredExpression | disease | LHGDN | Elevated serum APRIL levels in patients with systemic sclerosis: distinct profiles of systemic sclerosis categorized by APRIL and BAFF. | 17896803 | 2007 |