Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
0.050 Biomarker disease BEFREE SPLA2-IIA was found to be effective in detecting the presence of sepsis and bacterial infection in adults. 28671974 2017
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
0.050 GeneticVariation disease BEFREE Polymorphisms in TLR2 (rs3804099), TLR5 (rs5744105), IL10 (rs1800896), and PLA2G2A (rs1891320) genes were associated with sepsis. 20463618 2010
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
0.050 AlteredExpression disease BEFREE Pharmacological restriction of secretory group IIA phospholipase A(2) (sPLA(2)-IIA) expression is thought to be beneficial in the treatment of inflammatory diseases such as sepsis and septic shock. 17936881 2008
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
0.050 AlteredExpression disease BEFREE A significant increase in cPLA(2) activity, protein expression, and total PLA(2) activity in neutrophils was detected during sepsis. mRNA levels, detected by reverse transcriptase-polymerase chain reaction, were significantly higher during sepsis, indicating that the increase in the amount of cPLA(2) is regulated on the mRNA level. 10627477 2000
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A
0.050 Biomarker disease BEFREE Group II PLA2 has been implicated in inflammatory processes in both man and other animals and has been shown to be involved in inflammatory conditions, such as arthritis and sepsis. 8636402 1996