×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
AlteredExpression
group
LHGDN
Gastrin and c-met protein expression were significantly higher in gastric tumor tissue than in IM (P<0.0001).
14719064
2004
×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
Biomarker
group
BEFREE
The HGF-c-MET pathway plays a pivotal role in gastric tumor growth, invasion, metastasis and angiogenesis.
15026993
2004
×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
Biomarker
group
BEFREE
A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors .
21500189
2012
×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
Biomarker
group
BEFREE
MET status in synchronous liver metastasis (N = 36) was correlated with primary stomach tumors .
29790169
2018
×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
AlteredExpression
group
BEFREE
Finally, MET expression was evaluated by immunohistochemistry in a stomach tumor tissue microarray (TMA).
25874496
2015
×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
Biomarker
group
CTD_human
Antitumor action of the MET tyrosine kinase inhibitor crizotinib (PF-02341066) in gastric cancer positive for MET amplification.
22729845
2012
×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
GenomicAlterations
group
CGI
×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
AlteredExpression
group
BEFREE
Patients with positive c-MET expression had significantly shorter PFS (11.5 vs. 17.6 months, P = 0.039) and OS (17.0 vs. 24.3 months, P = 0.043), and had gastric tumors with a larger MTV (70.8 ± 53.11 vs. 41.1 ± 52.32, P = 0.034) and TLG (428.39 ± 442.95 vs. 205.7 ± 354.40, P = 0.039), compared with those with negative c-MET expression.
31395059
2019
×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
Biomarker
group
CTD_human
MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib.
22042947
2011
×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
AlteredExpression
group
BEFREE
However, several factors can trigger such MET upregulation in a manner independent of HGF, suggesting that gastric tumors with MET overexpression are not necessarily MET driven.
26690587
2016
×
Entrez Id:
4233
Gene Symbol:
MET
MET
0.580
Biomarker
group
BEFREE
Deregulated signaling via the MET receptor tyrosine kinase is abundant in gastric tumors , with up to 80% of cases displaying aberrant MET expression.
27185371
2016