×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
0.700
GeneticVariation
group
BEFREE
Also, eIF2α-P stimulation by the phosphatase inhibitor SAL003 substantially increases Trastuzumab potency in resistant HER2 + breast and gastric tumors .
31086176
2019
×
Entrez Id:
2064
Gene Symbol:
ERBB2
ERBB2
0.700
GeneticVariation
group
LHGDN
A single nucleotide polymorphism in the transmembrane domain coding region of HER-2 is associated with development and malignant phenotype of gastric cancer.
14520697
2003
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.640
GeneticVariation
group
BEFREE
These results suggest that genetic alteration of a region of APC commonly mutated in colorectal cancer is not a common event during sporadic gastric tumor development, at least in patients from North-Central Italy.
8649856
1996
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.640
GeneticVariation
group
CLINVAR
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.640
GeneticVariation
group
BEFREE
Mutations in the human APC gene are linked to familial adenomatous polyposis and to the progression of sporadic colorectal and gastric tumors .
8259518
1993
×
Entrez Id:
324
Gene Symbol:
APC
APC
0.640
GeneticVariation
group
BEFREE
Endoscopic findings of GN and background mucosa, and histopathological findings, including phenotypic expression of GN and mutation locus of adenomatous polyposis coli (APC ) gene, were evaluated.
31411765
2019
×
Entrez Id:
5290
Gene Symbol:
PIK3CA
PIK3CA
0.620
GeneticVariation
group
BEFREE
Only when the tumors were located in the middle-third of stomach, tumor with mutations of the PIK3CA gene or mutations of the PI3K/AKT pathway genes were associated with more EBV infection than those without mutations.
26701847
2016
×
Entrez Id:
2263
Gene Symbol:
FGFR2
FGFR2
0.620
GeneticVariation
group
CLINVAR
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
GeneticVariation
group
LHGDN
Genetic alterations of the MYH gene in gastric cancer.
15273732
2004
×
Entrez Id:
1316
Gene Symbol:
KLF6
KLF6
0.610
GeneticVariation
group
LHGDN
Genetic alterations of the KLF6 gene in gastric cancer.
15824733
2005
×
Entrez Id:
4595
Gene Symbol:
MUTYH
MUTYH
0.610
GeneticVariation
group
CLINVAR
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Founder and recurrent CDH1 mutations in families with hereditary diffuse gastric cancer.
17545690
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Germline E-cadherin mutations in hereditary diffuse gastric cancer: assessment of 42 new families and review of genetic screening criteria.
15235021
2004
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
A novel mutation in the E-cadherin gene in the first family with hereditary diffuse gastric cancer reported in Spain.
16870389
2006
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Association between CDH1 haplotypes and gastric cancer risk in a Japanese population.
17852867
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Single nucleotide polymorphisms in the promoter region of the E-cadherin gene in gastric cancer: case-control study in a young Mexican population.
17549573
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: a case control study in an Italian population.
18482459
2008
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
E-cadherin and hereditary diffuse gastric cancer.
17981184
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Germline E-cadherin mutations in familial lobular breast cancer.
17660459
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Hereditary diffuse gastric cancer and E-cadherin: description of the first germline mutation in an Italian family.
17126523
2007
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Association of CDH1 haplotypes with susceptibility to sporadic diffuse gastric cancer.
12444556
2002
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Hereditary diffuse gastric cancer: association with lobular breast cancer.
18046629
2008
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
CDH1/E-cadherin germline mutations in early-onset gastric cancer.
16801346
2006
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
Characterization of a recurrent germ line mutation of the E-cadherin gene: implications for genetic testing and clinical management.
16061854
2005
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.600
GeneticVariation
group
LHGDN
E-cadherin gene variants in gastric cancer families whose probands are diagnosed with diffuse gastric cancer.
12216071
2002