×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
GeneticVariation
group
BEFREE
Among germline TP53 mutation carriers, increased residual transcriptional activity is correlated with prolonged lifetime cancer survival and delayed tumor onset, and males are more prone to develop brain and gastric tumors .
30089713
2018
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
GeneticVariation
group
LHGDN
A p53 genetic polymorphism of gastric cancer: difference between early gastric cancer and advanced gastric cancer.
17072987
2006
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
AlteredExpression
group
LHGDN
Maspin and p53 protein expression in gastric adenocarcinoma and its clinical applications.
18091326
2008
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
GeneticVariation
group
BEFREE
Nevertheless, C carriers with a high D17S250 microsatellite instability (TP53 gene) show a higher risk to develop gastric tumors (P = 0.0453; OR: 4.1556-IC95%: 0.9716-17.7728), suggesting that the mutate TP53 gene may fail in control and inhibition of Survivin expression, favoring the gastric carcinogenesis.
21161671
2011
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
Biomarker
group
LHGDN
p53 is an indicator of tumor progression in early but not advanced gastric carcinomas.
18251181
2008
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
Biomarker
group
HPO
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
Biomarker
group
BEFREE
In humans, we found SRF and Enigma coexpressed with MDM2 but not p53 in several liver and stomach tumors .
21060154
2010
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
AlteredExpression
group
LHGDN
The evaluation of gastric cancer sensitivity to 5-FU/CDDP in terms of induction of apoptosis: time- and p53 expression-dependency of anti-cancer drugs.
16077963
2005
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
GeneticVariation
group
CLINVAR
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
GeneticVariation
group
BEFREE
Our findings indicate that mutations of the p53 gene are relatively rare in primary gastric tumors but appear to be relatively frequent in cell lines derived from metastatic lesions.
1676761
1991
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
GeneticVariation
group
BEFREE
Deletion of one copy of FBXW7 and TP53 was observed in 45.5% and 21.2% of gastric tumors , respectively.
24053468
2013
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
Biomarker
group
LHGDN
Clinicopathologic significance of HIF-1alpha, p53, and VEGF expression and preoperative serum VEGF level in gastric cancer.
18452596
2008
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
GeneticVariation
group
LHGDN
Prognostic role of p53 codon 72 polymorphism in gastric cancer patients treated with fluorouracil-based adjuvant chemotherapy.
18357466
2008
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
GeneticVariation
group
LHGDN
P53 codon 72 polymorphism and gastric cancer: a meta-analysis of the literature.
17546594
2007
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
Biomarker
group
LHGDN
Overexpression of hypoxia-inducible factor 1alpha and p53 is a marker for an unfavorable prognosis in gastric cancer.
16951228
2006
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
Biomarker
group
LHGDN
Expression of p53, inducible nitric oxide synthase and vascular endothelial growth factor in gastric precancerous and cancerous lesions: correlation with clinical features.
11978184
2002
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
Biomarker
group
BEFREE
The data on p53 abnormalities, when considered separately, could be of relative value for predicting the behavior of gastric tumors .
17436385
2007
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
Biomarker
group
CTD_human
Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes.
22484628
2012
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
AlteredExpression
group
BEFREE
Increased levels of TRIM59 in human gastric tumors correlated with reduced expression of P53 target genes.
25046164
2014
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
AlteredExpression
group
LHGDN
[Significance of COX-2, p53, proliferating cell nuclear antigen and nm23 expressions in gastric cancer and its behavior].
12452062
2002
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
Biomarker
group
LHGDN
Restoration of tumor suppressor miR-34 inhibits human p53-mutant gastric cancer tumorspheres.
18803879
2008
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
Biomarker
group
CTD_human
Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer.
24816253
2014
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
GeneticVariation
group
LHGDN
Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer.
17638920
2007
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
AlteredExpression
group
LHGDN
Helicobacter pylori infection generated gastric cancer through p53-Rb tumor-suppressor system mutation and telomerase reactivation.
12508351
2003
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.500
GeneticVariation
group
LHGDN
P53 codon 72 polymorphism and risk of gastric cancer in a Chinese population.
15069555
2004