Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6514
Gene Symbol: SLC2A2
SLC2A2 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 1728
Gene Symbol: NQO1
NQO1 		0.300 Therapeutic disease CTD_human Increased vulnerability to β-cell destruction and diabetes in mice lacking NAD(P)H:quinone oxidoreductase 1. 23458895 2013
Entrez Id: 581
Gene Symbol: BAX
BAX 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1 		0.300 Biomarker disease CTD_human Altered matrix metalloproteinases and tissue inhibitors of metalloproteinases in embryos from diabetic rats during early organogenesis. 21963884 2011
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Biomarker disease CTD_human Protective effect of Gui Qi mixture on the progression of diabetic nephropathy in rats. 17177138 2006
Entrez Id: 7351
Gene Symbol: UCP2
UCP2 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Biomarker disease CTD_human Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance. 18375438 2008
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1 		0.300 Biomarker disease CTD_human Modulations of cytochrome P450 expression in diabetic mice by berberine. 22342832 2012
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker disease CTD_human Heat shock protein 70 is necessary to improve mitochondrial bioenergetics and reverse diabetic sensory neuropathy following KU-32 therapy. 24263156 2014
Entrez Id: 4217
Gene Symbol: MAP3K5
MAP3K5 		0.300 Biomarker disease CTD_human 14-3-3 protein regulates Ask1 signaling and protects against diabetic cardiomyopathy. 18342293 2008
Entrez Id: 7132
Gene Symbol: TNFRSF1A
TNFRSF1A 		0.300 Therapeutic disease CTD_human Polyethylene glycolated recombinant TNF receptor I improves insulitis and reduces incidence of spontaneous and cyclophosphamide-accelerated diabetes in nonobese diabetic mice. 12193562 2002
Entrez Id: 4240
Gene Symbol: MFGE8
MFGE8 		0.300 Biomarker disease CTD_human Induction of lactadherin mediates the apoptosis of endothelial cells in response to advanced glycation end products and protective effects of grape seed procyanidin B2 and resveratrol. 21505870 2011
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Biomarker disease CTD_human Increased renal production of angiotensin II and thromboxane B2 in conscious diabetic rats. 15831366 2005
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2 		0.300 Biomarker disease CTD_human Altered matrix metalloproteinases and tissue inhibitors of metalloproteinases in embryos from diabetic rats during early organogenesis. 21963884 2011
Entrez Id: 2309
Gene Symbol: FOXO3
FOXO3 		0.300 Biomarker disease CTD_human Resveratrol prevents renal lipotoxicity and inhibits mesangial cell glucotoxicity in a manner dependent on the AMPK-SIRT1-PGC1α axis in db/db mice. 23090186 2013
Entrez Id: 7351
Gene Symbol: UCP2
UCP2 		0.300 Biomarker disease CTD_human Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. 16123366 2005
Entrez Id: 3953
Gene Symbol: LEPR
LEPR 		0.300 Biomarker disease CTD_human INT131: a selective modulator of PPAR gamma. 19452630 2009
Entrez Id: 1375
Gene Symbol: CPT1B
CPT1B 		0.300 Biomarker disease CTD_human Impaired expression of NADH dehydrogenase subunit 1 and PPARgamma coactivator-1 in skeletal muscle of ZDF rats: restoration by troglitazone. 14563825 2004
Entrez Id: 653361
Gene Symbol: NCF1
NCF1 		0.300 Biomarker disease CTD_human Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet. 14871415 2004
Entrez Id: 6548
Gene Symbol: SLC9A1
SLC9A1 		0.300 Biomarker disease CTD_human Effect of potent redox-modulating manganese porphyrin, MnTM-2-PyP, on the Na(+)/H(+) exchangers NHE-1 and NHE-3 in the diabetic rat. 20003708 2009
Entrez Id: 6517
Gene Symbol: SLC2A4
SLC2A4 		0.300 Biomarker disease CTD_human Troglitazone improves GLUT4 expression in adipose tissue in an animal model of obese type 2 diabetes mellitus. 11947963 2002