Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5027
Gene Symbol: P2RX7
P2RX7
0.010 GeneticVariation disease BEFREE This study investigated the P2X7 gene polymorphisms and protein levels in spinal TB. 29158203 2018
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
0.010 AlteredExpression disease BEFREE This variation may result in the decreased level of HLA-DQA1 mRNA and increased serum levels of IL-6 and TNF-α, which finally led the STB susceptibility. 29795056 2018
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.010 GeneticVariation disease BEFREE Association of IFNG gene polymorphisms with pulmonary tuberculosis but not with spinal tuberculosis in a Chinese Han population. 28867622 2017
Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1
0.010 AlteredExpression disease BEFREE This study intended to explore the expression of ADAMTS-4, VCAM-1, and TAK1 in cartilage tissue obtained from spinal tuberculosis patients and their inter-relationships, aiming to provide new treatment approaches for spinal tuberculosis. 28829887 2017
Entrez Id: 4312
Gene Symbol: MMP1
MMP1
0.010 GeneticVariation disease BEFREE Matrix metalloproteinase-1 promoter -1607 bp 1G/2G polymorphism associated with increased risk of spinal tuberculosis in Southern Chinese Han population. 28129430 2017
Entrez Id: 4318
Gene Symbol: MMP9
MMP9
0.010 AlteredExpression disease BEFREE MiR-133a could inhibit Collagen degradation by down-regulating MMP-9 expression to attenuate the destructive effects of spinal TB on intervertebral disc. 28739306 2017
Entrez Id: 6885
Gene Symbol: MAP3K7
MAP3K7
0.010 Biomarker disease BEFREE This study intended to explore the expression of ADAMTS-4, VCAM-1, and TAK1 in cartilage tissue obtained from spinal tuberculosis patients and their inter-relationships, aiming to provide new treatment approaches for spinal tuberculosis. 28829887 2017
Entrez Id: 6696
Gene Symbol: SPP1
SPP1
0.010 AlteredExpression disease BEFREE The TT genotype and low BMP-4 gene expression; the -66GG genotype and high OPN gene expression; and the ff genotype and low VDR gene expression significantly correlated with the clinical severity of spinal TB. 28376475 2017
Entrez Id: 652
Gene Symbol: BMP4
BMP4
0.010 AlteredExpression disease BEFREE The TT genotype and low BMP-4 gene expression; the -66GG genotype and high OPN gene expression; and the ff genotype and low VDR gene expression significantly correlated with the clinical severity of spinal TB. 28376475 2017
Entrez Id: 7182
Gene Symbol: NR2C2
NR2C2
0.010 AlteredExpression disease BEFREE Correlation analysis of ADAMTS-4, VCAM-1, and TAK1 expression in cartilage tissue from spine tuberculosis. 28829887 2017
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.010 GeneticVariation disease BEFREE Vitamin D deficiency, VDR, and TLR-2 polymorphisms did not affect the 6-month disability.Vitamin D deficiency and VDR gene polymorphisms are significantly more prevalent in people with pulmonary and spinal tuberculosis. 27124026 2016
Entrez Id: 54892
Gene Symbol: NCAPG2
NCAPG2
0.010 Biomarker disease BEFREE Among the 48 nonrespiratory specimens, the RAPID BAP-MTB assay was positive in one biopsy sample from a patient with lumbar tuberculous spondylitis and one pus sample from a patient with tuberculous cervical lymphadenopathy. 15472315 2004
Entrez Id: 64374
Gene Symbol: SIL1
SIL1
0.010 GeneticVariation disease BEFREE Among the 48 nonrespiratory specimens, the RAPID BAP-MTB assay was positive in one biopsy sample from a patient with lumbar tuberculous spondylitis and one pus sample from a patient with tuberculous cervical lymphadenopathy. 15472315 2004
Entrez Id: 4498
Gene Symbol: MT1JP
MT1JP
0.010 Biomarker disease BEFREE Among the 48 nonrespiratory specimens, the RAPID BAP-MTB assay was positive in one biopsy sample from a patient with lumbar tuberculous spondylitis and one pus sample from a patient with tuberculous cervical lymphadenopathy. 15472315 2004
Entrez Id: 11331
Gene Symbol: PHB2
PHB2
0.010 GeneticVariation disease BEFREE Among the 48 nonrespiratory specimens, the RAPID BAP-MTB assay was positive in one biopsy sample from a patient with lumbar tuberculous spondylitis and one pus sample from a patient with tuberculous cervical lymphadenopathy. 15472315 2004
Entrez Id: 3336
Gene Symbol: HSPE1
HSPE1
0.010 Biomarker disease BEFREE Mycobacterium tuberculosis chaperonin 10 stimulates bone resorption: a potential contributory factor in Pott's disease. 9334363 1997