Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9001
Gene Symbol: HAP1
HAP1 		0.200 Biomarker disease MGD
Entrez Id: 5320
Gene Symbol: PLA2G2A
PLA2G2A 		0.010 Biomarker disease BEFREE 'Mom-I don't want to hear it': Brain response to maternal praise and criticism in adolescents with major depressive disorder. 28338795 2017
Entrez Id: 6530
Gene Symbol: SLC6A2
SLC6A2 		0.400 GeneticVariation disease BEFREE 252 unrelated Caucasian patients (f = 142; m = 110) with major depression were genotyped for NET and 5-HTT polymorphisms. 20588071 2010
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4 		0.600 GeneticVariation disease BEFREE 252 unrelated Caucasian patients (f = 142; m = 110) with major depression were genotyped for NET and 5-HTT polymorphisms. 20588071 2010
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		0.380 Biomarker disease PSYGENET 47 patients with Major Depressive Disorder, treated with V 75 - 300 mg/day, underwent CYP2D6 genotyping using the INFINITI-CYP2D6 assay. 24660534 2014
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4 		0.600 GeneticVariation disease BEFREE 49 patients with major depression and SSRI treatment were genotyped for the 5-HTTLPR locus including the rs25531. 22086748 2012
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease BEFREE 5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression. 19590397 2009
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A 		0.400 GeneticVariation disease BEFREE 5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression. 19590397 2009
Entrez Id: 121278
Gene Symbol: TPH2
TPH2 		0.800 GeneticVariation disease BEFREE 5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression. 19590397 2009
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.600 GeneticVariation disease BEFREE 5-HTTLPR and <i>MTHFR 677C</i>>T polymorphisms and response to yoga-based lifestyle intervention in major depressive disorder: A randomized active-controlled trial. 30581206 2020
Entrez Id: 3776
Gene Symbol: KCNK2
KCNK2 		0.330 Biomarker disease CTD_human 5-HTTLPR genotype and gender, but not chronic fluoxetine administration, are associated with cortical TREK1 protein expression in rhesus macaques. 21871532 2011
Entrez Id: 4128
Gene Symbol: MAOA
MAOA 		0.400 Biomarker disease PSYGENET 94 patients of Caucasian descent with major depressive disorder (f = 61; DSM-IV) were analyzed for DNA methylation status at 43 MAO-A CpG sites via direct sequencing of sodium bisulfite treated DNA extracted from blood cells. 24809685 2015
Entrez Id: 4128
Gene Symbol: MAOA
MAOA 		0.400 PosttranslationalModification disease BEFREE 94 patients of Caucasian descent with major depressive disorder (f = 61; DSM-IV) were analyzed for DNA methylation status at 43 MAO-A CpG sites via direct sequencing of sodium bisulfite treated DNA extracted from blood cells. 24809685 2015
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.600 AlteredExpression disease BEFREE : The results suggest that the existence of major depression in pregnant women may negatively affect fetal circulating BDNF levels. 30905131 2019
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.090 Biomarker disease BEFREE Major depression is an important comorbidity in Alzheimer's disease, which is definitely associated with the apolipoprotein E (apo E) polymorphism. 16390369 2006
Entrez Id: 4128
Gene Symbol: MAOA
MAOA 		0.400 GeneticVariation disease BEFREE Major depressive disorder is a mediating factor between the monoamine oxidase A promoter polymorphism and telomeric length. 17417064 2007
Entrez Id: 2908
Gene Symbol: NR3C1
NR3C1 		0.600 GeneticVariation disease BEFREE Unipolar depression is associated with DNA variants of the NR3C1 gene in our population. 18286599 2008
Entrez Id: 2332
Gene Symbol: FMR1
FMR1 		0.310 Biomarker disease PSYGENET Major depression in females with the FMR1 premutation may not be characterized as an episodically chronic recurrent disorder as it is in community samples and may have a genetic basis given the relationship with CGG repeat length and lack of association with all child and most demographic factors. 18553360 2009
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.600 AlteredExpression disease BEFREE Major depressive disorder is a condition associated with dysregulated cytokine levels; among these, IL6. 27796193 2017
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1 		0.030 GeneticVariation disease BEFREE Major depressive disorder-associated SIRT1 locus affects the risk for suicide in women after middle age. 31176830 2019
Entrez Id: 5999
Gene Symbol: RGS4
RGS4 		0.020 AlteredExpression disease BEFREE RGS4 expression was not altered in the prefrontal cortex of subjects with major depressive disorder or in monkeys treated chronically with haloperidol. 11326297 2001
Entrez Id: 57113
Gene Symbol: TRPC7
TRPC7 		0.010 AlteredExpression disease BEFREE TRPC7 mRNA levels were significantly lower in BLCLs from BD-I patients with high BLCL [Ca(2+)]B compared with those showing normal [Ca(2+)]B (-33%, p =.017) and with BD-II patients (-48%, p =.003), major depressive disorder patients (-47%, p =.049) and healthy subjects (-33%, p =.038). 11690598 2001
Entrez Id: 4049
Gene Symbol: LTA
LTA 		0.310 GeneticVariation disease BEFREE Tumor necrosis factor-beta gene polymorphism may not be associated with major depressive disorder in the Korean population. 12519452 2003
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.090 GeneticVariation disease BEFREE Apolipoprotein E genotype and major depression in a community of older adults. The Cache County Study. 12701674 2003
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1 		0.010 Biomarker disease BEFREE Beta-1-adrenergic receptor gene in major depression: influence on antidepressant treatment response. 12815745 2003