Gene: HTR1A ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease BEFREE Preclinical and imaging/post-mortem studies in humans provide strong support for the involvement of HTR1A and HTR2A genes in MD. 23547754 2013
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease PSYGENET Somatodendritic 5-hydroxytryptamine1A (5-HT1A) autoreceptor function in major depression as assessed using the shift in electroencephalographic frequency spectrum with buspirone. 23809646 2014
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease BEFREE Somatodendritic 5-hydroxytryptamine1A (5-HT1A) autoreceptor function in major depression as assessed using the shift in electroencephalographic frequency spectrum with buspirone. 23809646 2014
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease BEFREE Transcriptional dys-regulation in anxiety and major depression: 5-HT1A gene promoter architecture as a therapeutic opportunity. 24180393 2014
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease PSYGENET Transcriptional dys-regulation in anxiety and major depression: 5-HT1A gene promoter architecture as a therapeutic opportunity. 24180393 2014
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease PSYGENET Genetic variation in brain-derived neurotrophic factor val66met allele is associated with altered serotonin-1A receptor binding in human brain. 24607934 2014
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease PSYGENET Interaction of 5-HTT and HTR1A gene polymorphisms in treatment responses to mirtazapine in patients with major depressive disorder. 24911443 2014
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 GeneticVariation disease BEFREE Interaction of 5-HTT and HTR1A gene polymorphisms in treatment responses to mirtazapine in patients with major depressive disorder. 24911443 2014
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 GeneticVariation disease BEFREE Differences in memory function between 5-HT1A receptor genotypes in patients with major depressive disorder. 26780922 2016
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease BEFREE The 5-HT1A receptor in Major Depressive Disorder. 26851834 2016
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 GeneticVariation disease BEFREE Association study of 5-HT1A, 5-HT2A polymorphisms with schizophrenia and major depressive disorder in the Han Chinese population. 27756686 2016
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease BEFREE The 5-HT1A autoreceptor mediates feedback inhibition of serotonin (5-HT) neurons, and is implicated in major depression. 29636529 2018
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease BEFREE A Novel Alternative Splicing Mechanism That Enhances Human 5-HT1A Receptor RNA Stability Is Altered in Major Depression. 30093565 2018
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 GeneticVariation disease BEFREE Thus, the 5-HT1A receptor gene illustrates the convergence of genetic, epigenetic and posttranscriptional mechanisms in gene expression, neurodevelopment and neuroplasticity, and major depression. 30807072 2019
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A 		0.400 Biomarker disease BEFREE Epistatic Interaction Between 5-HT1A and Vascular Endothelial Growth Factor Gene Polymorphisms in the Northern Chinese Han Population With Major Depressive Disorder. 31057436 2019