| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | group | BEFREE | protein/RNA levels of β-catenin (CTNNB1), its responsive markers [CyclinD1, c-Myc], Androgen receptor (AR), p27 and class-I HDACs were measured in matched UF/MM tissues or cell populations. | 31761932 | 2020 | ||||
|
0.080 | AlteredExpression | group | BEFREE | The AR protein expression and Ki-67 index in leiomyoma were ∼2- to 3-fold higher than that in normal myometrium. | 26342051 | 2016 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Moreover, CAG repeat analysis of the androgen receptor gene and an immunohistochemical analysis in the leiomyoma revealed clonal overgrowth of the cells which received X-inactivation on the non-affected allele. | 20951201 | 2011 | ||||
|
0.080 | GeneticVariation | group | BEFREE | We aimed to investigate the association between the AR gene CAG repeats and leiomyoma. | 15704521 | 2004 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Homozygous CAG repeats (22.0 +/- 2.3) in AR alleles were found in 5 of 30 cases, and either a large or small size of AR mRNA expression, were found in individual nodes of uterine leiomyoma, although paternal and maternal AR mRNAs from normal uterine myometrium were consistently expressed as AR alleles. | 10601839 | 2000 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Biallelic demethylation of the HUMARA microsatellite polymorphism was also found in one intramural leiomyoma. | 9176406 | 1997 | ||||
|
0.080 | AlteredExpression | group | BEFREE | TBS increased by estrogen are downregulated when testosterone is given along with estrogen, while androgen receptor mRNA increased by estrogen was not significantly altered by testosterone with estrogen in endometrium and leiomyoma. | 8049142 | 1994 | ||||
|
0.080 | Biomarker | group | BEFREE | Analysis of androgen receptor DNA reveals the independent clonal origins of uterine leiomyomata and the secondary nature of cytogenetic aberrations in the development of leiomyomata. | 7529041 | 1994 |