| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | AlteredExpression | group | BEFREE | Furthermore, transient overexpression of miR‑17‑5p induced a significant increase in the proliferation and a significant decrease in the apoptosis of HTMCs by affecting the expression of PTEN, and the apoptosis‑related proteins B‑cell lymphoma‑associated X protein (Bax), B‑cell lymphoma‑extra large (Bcl‑xL) and B‑cell lymphoma‑2 (Bcl‑2). | 30816540 | 2019 | ||||
|
0.070 | AlteredExpression | group | BEFREE | Significance of the microRNA‑17‑92 gene cluster expressed in B‑cell non‑Hodgkin's lymphoma. | 31322189 | 2019 | ||||
|
0.070 | Biomarker | group | BEFREE | Two miRNAs, hsa-miR-17-5p and hsa-miR-16-5p, were identified as having the highest associations with targeted mRNAs [such as B-cell lymphoma 2 (BCL2), small body size/mothers against decapentaplegic 3 (SMAD3) and suppressor of cytokine signaling 1 (SOCS1)] and pathways associated with epithelial-mesenchymal transitions and other processes linked with cancer metastasis (including cell cycle, adherence junctions and extracellular matrix-receptor interaction). mRNAs for two genes [HECT, UBA and WWE domain containing 1 (HUWE1) and BCL2] were found to have the highest associations with miRNAs, which were down-regulated in brain metastasis specimens of breast cancer. | 28739740 | 2017 | ||||
|
0.070 | Biomarker | group | BEFREE | Our results indicate that changes in miR-31 and miR-17-5p reflect the transformation of follicular lymphoma to an aggressive large B-cell lymphoma and may, along with their targets, be viable markers for this process. | 26997445 | 2016 | ||||
|
0.070 | Biomarker | group | BEFREE | The microRNA-17-92 cluster is an oncogene in human B cell lymphomas and lung cancers. | 20703102 | 2010 | ||||
|
0.070 | AlteredExpression | group | BEFREE | MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. | 18941111 | 2009 | ||||
|
0.070 | Biomarker | group | LHGDN | MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. | 18941111 | 2009 | ||||
|
0.070 | AlteredExpression | group | LHGDN | A microRNA polycistron as a potential human oncogene. | 15944707 | 2005 |