Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.400 | GeneticVariation | disease | BEFREE | GNB3 C825T and ACE I/D polymorphisms on the sodium-proton exchanger and the prevalence of essential hypertension in males. | 16314202 | 2006 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | The 825T allele of the GNB3 gene has been associated with essential hypertension and obesity in cross-sectional studies. | 14557282 | 2003 | ||||
|
0.400 | GeneticVariation | disease | BEFREE | GNB3 825 C>T is likely to be a significant risk factor for LVH but not for EH in the Emirati population, thereby strengthening the view that LVH is genetically a separate clinical entity. | 15614196 | 2005 | ||||
|
0.400 | Biomarker | disease | CTD_human | |||||||
|
0.400 | Biomarker | disease | BEFREE | Is the genetic variability of GNB3 a causative factor underlying the pathogenesis of essential hypertension? | 16600156 | 2006 | ||||
|
0.400 | Biomarker | disease | BEFREE | The 825-C/T polymorphism of the beta 3 subunit of the heterotrimeric G protein gene (GNB3) has been shown to be associated with essential hypertension in humans. | 11748488 | 2001 | ||||
|
0.400 | Biomarker | disease | BEFREE | To determine whether four potential genetic factors (polymorphisms in genes for alpha-adducin, beta-adducin, the G-protein beta-3 subunit and nitric oxide synthase) are important for the development of essential hypertension (EH) in Slovenian children and young adults with EH. | 16497648 | 2006 | ||||
|
0.400 | Biomarker | disease | BEFREE | The genes FTO and GNB3 are implicated in essential hypertension but their interaction remains to be explored. | 23691120 | 2013 | ||||
|
0.400 | Biomarker | disease | BEFREE | Our results demonstrate the potential use of a GNB3-specific antisense morpholino, as a pharmacogenetic therapy for essential hypertension. | 27028457 | 2016 |