Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
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0.070 | Biomarker | phenotype | BEFREE | The delayed Gaussian a-wave model is useful for characterizing abnormalities in the activation phase of cone phototransduction and can help explain flicker ERG abnormalities in early-stage diabetic retinopathy. | 30640972 | 2019 | ||||
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0.070 | Biomarker | phenotype | BEFREE | The cone response and flicker ERG response were decreased markedly only in the right eye. | 31096954 | 2019 | ||||
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0.070 | Biomarker | phenotype | BEFREE | Thus, the two flicker ERG techniques give comparable results, under both dark- and light-adapted conditions, and the flicker sweep method is faster to administer and analyze and may be less susceptible to blinking, breathing, and eye movement artifacts. | 29721938 | 2018 | ||||
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0.070 | Biomarker | phenotype | BEFREE | In this study, we recorded light- (photopic) and dark-adapted (scotopic) fERG data from 25 schizophrenia patients and 25 healthy control subjects to (1) determine if past key findings on abnormal photoreceptor and bipolar cell signaling could be replicated; (2) for the first time, examine retinal ganglion cell functioning using the photopic negative response of the fERG; (3) also for the first time, determine responsiveness of schizophrenia patients to a flickering stimulus, as an additional method to isolate cone photoreceptor function; and (4) determine if schizophrenia-related changes in the fERG could be detected using a portable hand-held ERG device. | 29745706 | 2018 | ||||
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0.070 | Biomarker | phenotype | BEFREE | For the scotopic flicker ERG, we found a significantly lower magnitude for Cln3 <sup>Δex7/8</sup> KI mice already at 6 months of age for low stimulus frequencies, while the difference declines with increasing frequency. | 29721970 | 2018 | ||||
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0.070 | Biomarker | phenotype | BEFREE | The results also suggest that the supernormal flicker ERG may be caused by changes in the electrical activities of retinal cells following a mild increase in the VEGF levels in eyes with CRVO. | 30550616 | 2018 | ||||
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0.070 | Biomarker | phenotype | BEFREE | Full-field single flash ERG was recordable but 30 Hz flicker ERG was not detectable. | 25096270 | 2014 |