Statistical correlation analysis showed RBMS3 to be negatively correlated with c-Myc (r = -0.384, p < 0.001) and not correlated with cytoplasmic β-catenin in the LSCC samples.
The present study suggests that simultaneous overexpression of β-catenin and cyclin D1 may be associated with poor overall survival irrespective of platinum-based adjuvant chemotherapy in stage IA-IIA squamous cell carcinoma of the lung.