G-to-A and C-to-T nucleotide changes, characteristic of APOBEC3G, were higher in CHD and CI than in CHB in genotype A haplotypes, but not in genotype D. The proportion of nt G-to-A <i>vs</i> A-to-G changes and C-to-T <i>vs</i> T-to-C changes in genotype A and D haplotypes in CHD patients showed no significant differences.
The expression levels of STAT-1 and APOBEC3G in the liver of CHB patients with a complete response to IFN-α are significantly higher than that of the patients with non-response to IFN-α treatment.