| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | GeneticVariation | disease | BEFREE | However, the use of DOACs in unusual VTE, including cerebral venous thrombosis (CVT) and splanchnic venous thrombosis (SVT), and in patients with biological thrombophilia including minor thrombophilia (Factor V Leiden and prothrombin G20210A), major innate thrombophilia (protein C and S deficiency, and antithrombin) and major acquired thrombophilia (antiphospholipid syndrome [APS]), remains controversial due to the paucity of available data. | 29402471 | 2018 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Prevalence and geographical variation of Factor V Leiden in patients with cerebral venous thrombosis: A meta-analysis. | 30157246 | 2018 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The presence of prothrombin 19911 A>G was investigated in a case–control study of 107 patients with cerebral thrombosis and factor V Leiden (n = 25), prothrombin 20210 GA (n = 47), without known thrombophilia (n = 35) and 842 healthy individuals with the corresponding coagulation profile. | 20482605 | 2010 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Genetic thrombophilic conditions such as those associated with Factor V Leiden (FVL) and the prothrombin mutant (PT G20210A) have been identified as risk factors for cerebral venous thrombosis (CVT). | 16155788 | 2006 | ||||
|
0.070 | Biomarker | disease | BEFREE | Lupus anticoagulant, factor V Leiden, and methylenetetrahydrofolate reductase gene mutation in a lupus patient with cerebral venous thrombosis. | 15293102 | 2004 | ||||
|
0.070 | Biomarker | disease | BEFREE | Hyperhomocysteinemia and other newly recognized inherited coagulation disorders (factor V Leiden and prothrombin gene mutation) in patients with idiopathic cerebral vein thrombosis. | 14707415 | 2004 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | We conclude that inherited APC resistance by a mutation in factor V Leiden is an important risk factor in non-fatal cerebral venous thrombosis. | 9553844 | 1998 |