Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 50940
Gene Symbol: PDE11A
PDE11A
0.100 Biomarker disease HPO
Entrez Id: 7048
Gene Symbol: TGFBR2
TGFBR2
0.100 Biomarker disease HPO
Entrez Id: 9049
Gene Symbol: AIP
AIP
0.100 Biomarker disease HPO
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 Biomarker disease HPO
Entrez Id: 6452
Gene Symbol: SH3BP2
SH3BP2
0.100 Biomarker disease HPO
Entrez Id: 1290
Gene Symbol: COL5A2
COL5A2
0.100 Biomarker disease HPO
Entrez Id: 2778
Gene Symbol: GNAS
GNAS
0.100 Biomarker disease HPO
Entrez Id: 5167
Gene Symbol: ENPP1
ENPP1
0.100 Biomarker disease HPO
Entrez Id: 8622
Gene Symbol: PDE8B
PDE8B
0.100 Biomarker disease HPO
Entrez Id: 8450
Gene Symbol: CUL4B
CUL4B
0.100 Biomarker disease HPO
Entrez Id: 1289
Gene Symbol: COL5A1
COL5A1
0.100 Biomarker disease HPO
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.100 CausalMutation disease CLINVAR
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A
0.100 Biomarker disease HPO
Entrez Id: 7046
Gene Symbol: TGFBR1
TGFBR1
0.100 Biomarker disease HPO
Entrez Id: 2006
Gene Symbol: ELN
ELN
0.040 Biomarker disease BEFREE The main differences observed when comparing skin with and without stretch marks were at depths between 75 and 95 μm, corresponding to the dermal-epidermal junction and dermis regions and showing differences between normal skin and stretched skin regarding collagen, collagen hydration, and elastin fibers. 31131982 2020
Entrez Id: 10882
Gene Symbol: C1QL1
C1QL1
0.040 Biomarker disease BEFREE CRF-producing cells in the central nucleus of amygdala (CeA) and oval division of the bed nucleus of stria terminalis (BNSTov) are also involved in stress adaptation and mood control. 31649527 2019
Entrez Id: 2006
Gene Symbol: ELN
ELN
0.040 GeneticVariation disease BEFREE Collagen type III and elastin genes polymorphism and the risk of nonsyndromic striae. 29498185 2019
Entrez Id: 10882
Gene Symbol: C1QL1
C1QL1
0.040 AlteredExpression disease BEFREE A selective THIP-induced activation of CRF-expressing neurons in the oval part of the bed nucleus of stria terminalis may constitute a novel mechanism for inducing plasticity in a population of VTA DA neurons and aversive behavioral states. 31178693 2019
Entrez Id: 10882
Gene Symbol: C1QL1
C1QL1
0.040 Biomarker disease BEFREE Control of cardiovascular responses to stress by CRF in the bed nucleus of stria terminalis is mediated by local NMDA/nNOS/sGC/PKG signaling. 29414029 2018
Entrez Id: 10882
Gene Symbol: C1QL1
C1QL1
0.040 Biomarker disease BEFREE CRF receptor type 2 neurons in the posterior bed nucleus of the stria terminalis critically contribute to stress recovery. 27550842 2017
Entrez Id: 2006
Gene Symbol: ELN
ELN
0.040 Biomarker disease BEFREE Because aldosterone applied alone stimulates both collagen and elastin deposition in cultures of fibroblasts and in cultures of skin explants derived from dermal stretch marks, we postulate that this steroid should be used in the treatment of damaged skin that loses its volume and elasticity. 20535129 2010
Entrez Id: 2006
Gene Symbol: ELN
ELN
0.040 AlteredExpression disease BEFREE These observations suggest that expression of collagens, elastin and fibronectin genes are apparently decreased, and that there is a marked alteration of fibroblast metabolism, in striae distensae. 7955466 1994
Entrez Id: 10804
Gene Symbol: GJB6
GJB6
0.030 AlteredExpression disease BEFREE We detected Cx26 and Cx30 expressions in the type I, II& V fibrocytes in the spiral ligament, fibrocytes of the spiral limbus, in the supporting cells of organ of Corti, inner and outer sulcus cells, and in the basal cells of the stria vascularis. 31421828 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.030 GeneticVariation disease BEFREE We previously showed that, in male mice, the estrogen receptor-α (<i>Esr1</i>) and aromatase (<i>Cyp19a1</i>) genes are essential to the sexually dimorphic formation of the anteroventral periventricular nucleus (AVPV) and the principal nucleus of the bed nucleus of the stria terminalis (BNSTp), but the estrogen receptor-β (<i>Esr2</i>) gene is not necessary. 29770127 2018
Entrez Id: 10804
Gene Symbol: GJB6
GJB6
0.030 AlteredExpression disease BEFREE Cx26 and Connexin-30 (Cx30) encode gap junction proteins expressed in supporting cells of the organ of Corti, the spiral limbus, stria vascularis, and in fibrocytes of the spiral ligament. 29911391 2018