Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.300 Biomarker disease CTD_human K-ras mutations in lung tumors and tumors from other organs are consistent with a common mechanism of ethylene oxide tumorigenesis in the B6C3F1 mouse. 17325976 2007
Entrez Id: 3219
Gene Symbol: HOXB9
HOXB9 		0.300 Biomarker disease CTD_human Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo. 27182052 2016
Entrez Id: 3624
Gene Symbol: INHBA
INHBA 		0.300 Biomarker disease CTD_human A high concentration of genistein down-regulates activin A, Smad3 and other TGF-β pathway genes in human uterine leiomyoma cells. 22228119 2012
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.030 Biomarker disease BEFREE In humans, a PMN gene signature correlated with improved survival in several cancer subtypes, including PTEN-deficient uterine cancer. 26678340 2015
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.030 Biomarker disease BEFREE In vitro and in vivo therapeutic experiments were carried out using PTEN-mutated and PTEN-wild-type models of uterine cancer alone and in combination with chemotherapy. 25833835 2015
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.030 Biomarker disease BEFREE Inhibitors of the PI3K pathway are in clinical testing in patients with solid tumors, including uterine cancer. 21903247 2011
Entrez Id: 3170
Gene Symbol: FOXA2
FOXA2 		0.020 Biomarker disease BEFREE FOXA2 is considered to be a driver gene in uterine cancers, functioning as a haploinsufficient tumor suppressor. 30091462 2018
Entrez Id: 3170
Gene Symbol: FOXA2
FOXA2 		0.020 Biomarker disease BEFREE Collectively, the findings of the current study provide compelling genetic evidence that FOXA2 is a pathogenic driver gene in the etiology of primary uterine cancers, including UCSs.Cancer 2018;124:65-73.© 2017 American Cancer Society. 28940304 2018
Entrez Id: 5518
Gene Symbol: PPP2R1A
PPP2R1A 		0.020 Biomarker disease BEFREE We sequenced the PPP2R1A in 22 cell line models of uterine cancer and 10 primary cancers. 21882256 2012
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.020 Biomarker disease BEFREE LKB1 as a Tumor Suppressor in Uterine Cancer: Mouse Models and Translational Studies. 27910069 2017
Entrez Id: 5241
Gene Symbol: PGR
PGR 		0.020 Biomarker disease BEFREE Progesterone receptor (PR) is strongly associated with disease prognosis and therapeutic efficacy in hormone-related diseases such as endometriosis and breast, ovarian, and uterine cancers. 21972997 2011
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.020 Biomarker disease BEFREE Moreover, clinical trials of HER2-directed therapies, including trastuzumab, pertuzumab, and lapatinib in ovarian and uterine cancers have been largely disappointing. 25220628 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.020 Biomarker disease BEFREE L1CAM and HER2 Expression in Early Endometrioid Uterine Cancer. 28221216 2017
Entrez Id: 5241
Gene Symbol: PGR
PGR 		0.020 Biomarker disease BEFREE Inhibiting Nuclear Phospho-Progesterone Receptor Enhances Antitumor Activity of Onapristone in Uterine Cancer. 29237804 2018
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.020 Biomarker disease BEFREE The serine/threonine kinase LKB1 has been identified as a potent suppressor of uterine cancer, but the biological modes of action of LKB1 in this context remain incompletely understood. 26413869 2015
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.010 Biomarker disease BEFREE Inhibitors of the PI3K pathway are in clinical testing in patients with solid tumors, including uterine cancer. 21903247 2011
Entrez Id: 407007
Gene Symbol: MIR222
MIR222 		0.010 Biomarker disease BEFREE It is expected that miR-222 will be an indicator and target for the treatment and prognosis of uterine cancer. 30008859 2018
Entrez Id: 7517
Gene Symbol: XRCC3
XRCC3 		0.010 Biomarker disease BEFREE Nuclear proteomics with XRCC3 knockdown to reveal the development of doxorubicin-resistant uterine cancer. 24675091 2014
Entrez Id: 1490
Gene Symbol: CCN2
CCN2 		0.010 Biomarker disease BEFREE Role of CTGF in Sensitivity to Hyperthermia in Ovarian and Uterine Cancers. 27806300 2016
Entrez Id: 84692
Gene Symbol: CCDC54
CCDC54 		0.010 Biomarker disease BEFREE In Vitro Assessment of the Expression and T Cell Immunogenicity of the Tumor-Associated Antigens BORIS, MUC1, hTERT, MAGE-A3 and Sp17 in Uterine Cancer. 27618037 2016
Entrez Id: 4191
Gene Symbol: MDH2
MDH2 		0.010 Biomarker disease BEFREE Mitochondrial proteomics with siRNA knockdown to reveal ACAT1 and MDH2 in the development of doxorubicin-resistant uterine cancer. 25639359 2015
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		0.010 Biomarker disease BEFREE Expression of PDGFRα was examined in uterine cancer clinical samples and cell lines, and biologic effects of PDGFRα inhibition were evaluated using in vitro (cell viability, apoptosis, and invasion) and in vivo (orthotopic) models of uterine cancer. 24634380 2014
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG 		0.010 Biomarker disease BEFREE Inhibitors of the PI3K pathway are in clinical testing in patients with solid tumors, including uterine cancer. 21903247 2011
Entrez Id: 10763
Gene Symbol: NES
NES 		0.010 Biomarker disease BEFREE The relationship between nestin and PFS was independent of stage, LVSI and risk categorization but not type of UC. 26718725 2016
Entrez Id: 38
Gene Symbol: ACAT1
ACAT1 		0.010 Biomarker disease BEFREE Mitochondrial proteomics with siRNA knockdown to reveal ACAT1 and MDH2 in the development of doxorubicin-resistant uterine cancer. 25639359 2015