Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 70
Gene Symbol: ACTC1
ACTC1
0.010 GeneticVariation disease BEFREE GJD2, and ACTC1 genes with pathological myopia in a Chinese Han population. 23834555 2015
Entrez Id: 443
Gene Symbol: ASPA
ASPA
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 654
Gene Symbol: BMP6
BMP6
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 64084
Gene Symbol: CLSTN2
CLSTN2
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 1501
Gene Symbol: CTNND2
CTNND2
0.010 GeneticVariation disease BEFREE Specific polymorphisms in the CTNND2 gene and 11q24.1 genomic region were found to be significantly associated with pathological myopia in this Chinese population, further supporting the idea that these genomic regions carry susceptibility loci for this disease. 22759899 2012
Entrez Id: 57706
Gene Symbol: DENND1A
DENND1A
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 1665
Gene Symbol: DHX15
DHX15
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 22943
Gene Symbol: DKK1
DKK1
0.010 AlteredExpression disease BEFREE Additionally, we found that the DKK1 levels were positively correlated with HGF (β = 0.268, <i>P</i> = .032), and TIMP-3 (β = 0.209, <i>P</i> = .047) levels, as well as with axial length (β = 0.714, <i>P</i> < .0001) in the pathological myopia group.<b>Conclusions</b>: Elevated levels of DKK1 were found in the eyes with elongated axial length. 31335221 2020
Entrez Id: 2313
Gene Symbol: FLI1
FLI1
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 57369
Gene Symbol: GJD2
GJD2
0.010 Biomarker disease BEFREE GJD2, and ACTC1 genes with pathological myopia in a Chinese Han population. 23834555 2015
Entrez Id: 3082
Gene Symbol: HGF
HGF
0.010 AlteredExpression disease BEFREE Additionally, we found that the DKK1 levels were positively correlated with HGF (β = 0.268, <i>P</i> = .032), and TIMP-3 (β = 0.209, <i>P</i> = .047) levels, as well as with axial length (β = 0.714, <i>P</i> < .0001) in the pathological myopia group.<b>Conclusions</b>: Elevated levels of DKK1 were found in the eyes with elongated axial length. 31335221 2020
Entrez Id: 284217
Gene Symbol: LAMA1
LAMA1
0.010 GeneticVariation disease BEFREE We suggest that LAMA1 SNP rs2089760 plays an important role in the development of PM. 26862816 2016
Entrez Id: 105374266
Gene Symbol: LINC01991
LINC01991
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 399715
Gene Symbol: LINC02649
LINC02649
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 729305
Gene Symbol: LINC02714
LINC02714
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 4036
Gene Symbol: LRP2
LRP2
0.200 Biomarker disease MGD
Entrez Id: 4285
Gene Symbol: MIPEP
MIPEP
0.100 GeneticVariation disease GWASCAT Genetic variants at 13q12.12 are associated with high myopia in the Han Chinese population. 21640322 2011
Entrez Id: 399959
Gene Symbol: MIR100HG
MIR100HG
0.100 GeneticVariation disease GWASCAT A genome-wide association analysis identified a novel susceptible locus for pathological myopia at 11q24.1. 19779542 2009
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.010 Biomarker disease BEFREE The peripheral blood mononuclear cells (PBMCs) from a patient with PM were successfully reprogrammed to induced pluripotent stem cells (iPSCs) using integration-free method, Sendai viral (SeV) vectors expressing OCT4, SOX2, KLF4 and C-MYC. 30611020 2019
Entrez Id: 4658
Gene Symbol: MYP2
MYP2
0.010 Biomarker disease BEFREE We carried out a literature review (September 2015) of all English-language articles in PubMed resulting from searches of the following terms: "choroidal neovascularization" AND "myopia" OR "myopic macular degeneration" OR "degenerative myopia" OR "myopic maculopathy" OR "myopic retinopathy" OR "pathological myopia" OR "pathologic myopia." 28655539 2017
Entrez Id: 89795
Gene Symbol: NAV3
NAV3
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 5362
Gene Symbol: PLXNA2
PLXNA2
0.010 Biomarker disease BEFREE We describe the OCT-A features of myopic CNV secondary to pathological myopia and demonstrate its high sensitivity and specificity for neovascular detection. 27531357 2017
Entrez Id: 5371
Gene Symbol: PML
PML
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 5789
Gene Symbol: PTPRD
PTPRD
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012
Entrez Id: 5799
Gene Symbol: PTPRN2
PTPRN2
0.100 GeneticVariation disease GWASCAT A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population. 23049088 2012