Furthermore, MALAT1 directly binds to SFPQ (Splicing Factor Proline and Glutamine Rich) protein, indicating its multifaceted roles in ACC pathophysiology.
A total of 956 lncRNAs were differentially expressed between ACC and NAC, including known carcinogenesis-related lncRNAs such as H19, GAS5, MALAT1 and PRINS (P≤0.05); 85 lncRNAs were differentially expressed between ACC and ACA (P≤0.05).