Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | AlteredExpression | disease | BEFREE | Although the predominant phenotype of the MYB-NFIB GEMM was B-cell leukemia, we also generated a MYB-activated ACC-like mammary tumor cell line. | 31606723 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | It is concluded that MYBL1 alterations are detected in primary cutaneous ACC but are apparently less common compared with MYB and NFIB alterations. | 29570128 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | We also analyzed ACC-specific MYB and MYBL1 gene rearrangements by fluorescence in situ hybridization (FISH). | 29496310 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The t(6;9) (q22-23;p23-24) translocation, resulting in a MYB-NFIB gene fusion has been found in ACCs from the salivary glands and other organs. | 27859477 | 2017 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Reciprocal MYB and MYBL1 expression was consistently found in ACCs. | 26631609 | 2016 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Interestingly, tumors with MYB and MYBL1 translocations displayed similar gene expression profiles, and the combined MYB and MYBL1 expression correlated with outcome, suggesting that the related MYB proteins are interchangeable oncogenic drivers in ACC. | 26631070 | 2016 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | The majority of ACCs express the oncogenic transcription factor MYB (also c-myb), often in the context of a MYB gene rearrangement. | 27566443 | 2016 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | A significant portion of adenoid cystic carcinoma (ACC) cases are characterized by a t(6;9)(q22-23;p23-24) translocation that originates a MYB-NFIB fusion oncogene. | 26309189 | 2015 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Many ACCs have a t(6;9) chromosomal translocation resulting in a MYB-NFIB fusion gene, but the clinical significance is unclear. | 25963073 | 2015 |