Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 9429
Gene Symbol: ABCG2
ABCG2 		0.300 Biomarker disease CTD_human Downregulation of breast cancer resistance protein in colon adenomas reduces cellular xenobiotic resistance and leads to accumulation of a food-derived carcinogen. 21544799 2011
Entrez Id: 9049
Gene Symbol: AIP
AIP 		0.300 Biomarker disease CTD_human Aryl-hydrocarbon receptor activity modulates prolactin expression in the pituitary. 22975028 2012
Entrez Id: 240
Gene Symbol: ALOX5
ALOX5 		0.300 Biomarker disease CTD_human Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model. 18927292 2008
Entrez Id: 23600
Gene Symbol: AMACR
AMACR 		0.300 Biomarker disease CTD_human Variants in the alpha-Methylacyl-CoA racemase gene and the association with advanced distal colorectal adenoma. 17684125 2007
Entrez Id: 324
Gene Symbol: APC
APC 		0.300 Biomarker disease CTD_human One dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) induces tumours in Min/+ mice by truncation mutations or LOH in the Apc gene. 12034317 2002
Entrez Id: 324
Gene Symbol: APC
APC 		0.300 Biomarker disease CTD_human Crypt stem cells as the cells-of-origin of intestinal cancer. 19092804 2009
Entrez Id: 324
Gene Symbol: APC
APC 		0.300 Biomarker disease CTD_human Short-term carcinogenicity testing of a potent murine intestinal mutagen, 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP), in Apc1638N transgenic mice. 9111214 1997
Entrez Id: 324
Gene Symbol: APC
APC 		0.300 Biomarker disease CTD_human Neonatal exposure to the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine via breast milk or directly induces intestinal tumors in multiple intestinal neoplasia mice. 10383901 1999
Entrez Id: 324
Gene Symbol: APC
APC 		0.300 Biomarker disease CTD_human The conserved protective cyclic AMP-phosphodiesterase function PDE4B is expressed in the adenoma and adjacent normal colonic epithelium of mammals and silenced in colorectal cancer. 30188895 2018
Entrez Id: 476
Gene Symbol: ATP1A1
ATP1A1 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension. 23416519 2013
Entrez Id: 476
Gene Symbol: ATP1A1
ATP1A1 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. 23913004 2013
Entrez Id: 489
Gene Symbol: ATP2A3
ATP2A3 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. 23913004 2013
Entrez Id: 492
Gene Symbol: ATP2B3
ATP2B3 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension. 23416519 2013
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.300 Biomarker disease CTD_human Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice. 10223192 1999
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.300 Biomarker disease CTD_human Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice. 10426811 1999
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1 		0.300 Biomarker disease CTD_human Altered bcl-2 family expression during non-genotoxic hepatocarcinogenesis in mice. 10426811 1999
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D 		0.300 Biomarker disease CTD_human Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism. 23913001 2013
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. 23913004 2013
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.300 Biomarker disease CTD_human Relationship of beta-catenin and Bcl-2 expression to sulindac-induced regression of intestinal tumors in Min mice. 10223192 1999
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.300 Biomarker disease CTD_human More frequent beta-catenin gene mutations in adenomas than in aberrant crypt foci or adenocarcinomas in the large intestines of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-treated rats. 10965019 2000
Entrez Id: 1545
Gene Symbol: CYP1B1
CYP1B1 		0.300 Biomarker disease CTD_human Understanding the role of xenobiotic-metabolism in chemical carcinogenesis using gene knockout mice. 11376689 2001
Entrez Id: 2697
Gene Symbol: GJA1
GJA1 		0.300 Biomarker disease CTD_human Altered expression of connexins in urethane-induced mouse lung adenomas. 16926031 2006
Entrez Id: 2705
Gene Symbol: GJB1
GJB1 		0.300 Biomarker disease CTD_human Altered expression of connexins in urethane-induced mouse lung adenomas. 16926031 2006
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.300 Biomarker disease CTD_human Hepatobiliary and gastrointestinal manifestations of acromegaly. 1611713 1992
Entrez Id: 3762
Gene Symbol: KCNJ5
KCNJ5 		0.300 Biomarker disease CTD_human Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. 23913004 2013