| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | disease | BEFREE | FLT3-ITD and MLL-PTD influence the expression of MDR-1, MRP-1, and BCRP mRNA but not LRP mRNA assessed with RQ-PCR method in adult acute myeloid leukemia. | 24030729 | 2014 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival. | 19240178 | 2009 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Clinical resistance to chemotherapy in acute myeloid leukemia (AML) is associated with the expression of the multidrug resistance (MDR) proteins P-glycoprotein, encoded by the MDR1/ABCB1 gene, multidrug resistant-related protein (MRP/ABCC1), the lung resistance-related protein (LRP), or major vault protein (MVP), and the breast cancer resistance protein (BCRP/ABCG2). | 17340137 | 2007 | ||||
|
0.080 | Biomarker | disease | BEFREE | Expression of the multidrug resistance proteins P-glycoprotein, encoded by the MDR1 gene, multidrug resistance-associated protein (MRP1) and the lung resistance-related protein or major vault protein (LRP/MVP) is associated with clinical resistance to chemotherapy in acute myeloid leukemia (AML). | 11986944 | 2002 | ||||
|
0.080 | Biomarker | disease | BEFREE | Modulation of not only Pgp but also MRP1 could be essential to attain this aim in adult AML. | 10419897 | 1999 | ||||
|
0.080 | Biomarker | disease | BEFREE | In this paper, we will review these recent data concerning the role of MRP1 in adult AML. | 10214864 | 1999 | ||||
|
0.080 | Biomarker | disease | BEFREE | Pgp and MRP activities using calcein-AM are prognostic factors in adult acute myeloid leukemia patients. | 9616142 | 1998 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | In two multidrug resistant (MDR) sublines of the HL-60 human acute myeloid leukemia (AML) cell line which overexpress MRP but not P-glycoprotein, the assay detects elevated levels of MRP mRNA (4- to 8-fold) relative to the drug-sensitive parental cells (designated HL-60/W). | 8558937 | 1996 |