Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (pHPT) is characterised by an inappropriate over production of parathyroid hormone and it is the most frequent pathological condition of the parathyroid glands. 23093699 2013
Entrez Id: 5979
Gene Symbol: RET
RET
0.100 Biomarker disease BEFREE Primary hyperparathyroidism (PHPT) occurs sporadically, but occasionally it may be a feature of a familial condition, such as multiple endocrine neoplasia type 1 (MEN1), MEN2A, or the HPT-jaw tumor syndrome (HPT-JT), and familial hypocalciuric hypercalcemia/neonatal severe hyperparathyroidism (FHH/NSHPT). 23652676 2013
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 GeneticVariation disease BEFREE Primary hyperparathyroidism (HPT) is one of the most common endocrine disorders, defined by hypersecretion of parathormone. 24595969 2015
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (pHPT) is a common endocrine disease characterized by excessive secretion of parathyroid hormone and an increased level of serum calcium. 27071708 2016
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (PHPT) is a common disorder in which parathyroid hormone (PTH) is excessively secreted from one or more of the four parathyroid glands. 27194212 2016
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (PHPT) is a common endocrine disease characterized by parathyroid hormone excess and hypercalcemia and caused by hypersecreting parathyroid glands. 27745835 2016
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 AlteredExpression disease BEFREE Primary hyperparathyroidism is characterized by increased levels of serum calcium and parathyroid hormone. 27847113 2017
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (pHPT) is commonly treated with targeted parathyroidectomy (PTX) guided by preoperative imaging and intraoperative parathormone monitoring. 27979480 2017
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism is a condition with hypercalcemia and elevated parathyroid hormone (PTH). 28277104 2017
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (pHPT) is characterised by increased parathyroid hormone (PTH) secretion and consequently increased plasma calcium. 28315908 2017
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (PHPT) is defined by inappropriate elevation of parathormone, caused by parathyroid hyperplasia, also known as multi-gland disease (MGD), parathyroid adenoma (PA), or parathyroid carcinoma (PC). 28362510 2018
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (HPT) is a metabolic disease caused by the excessive secretion of parathyroid hormone from 1 or more neoplastic parathyroid glands. 28476229 2017
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (pHPT) is a common endocrinopathy resulting from inappropriately high PTH secretion. 29330338 2018
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism is commonly caused by excess production of parathyroid hormone from sporadic parathyroid adenomas. 29982334 2018
Entrez Id: 4221
Gene Symbol: MEN1
MEN1
0.200 Biomarker disease BEFREE Primary hyperparathyroidism associated with MEN 1: Experience in 71 cases. 30056973 2018
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 AlteredExpression disease BEFREE Primary hyperparathyroidism (pHPT) is the third most common endocrine disease and is characterized by hypercalcaemia and elevated or inappropriately 'normal' levels of the parathyroid hormone (PTH). 30289185 2019
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 AlteredExpression disease BEFREE Primary hyperparathyroidism (PHPT) is a condition where elevated PTH levels lead to bone loss, in part through increased production of the osteoclastogenic factor IL-17A, by bone marrow (BM) T-helper 17 (Th17) cells, a subset of helper CD4+ T cells. 30399207 2019
Entrez Id: 3605
Gene Symbol: IL17A
IL17A
0.010 AlteredExpression disease BEFREE Primary hyperparathyroidism (PHPT) is a condition where elevated PTH levels lead to bone loss, in part through increased production of the osteoclastogenic factor IL-17A, by bone marrow (BM) T-helper 17 (Th17) cells, a subset of helper CD4+ T cells. 30399207 2019
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterised by hypercalcaemia and parathormone increase. 30459009 2020
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (PHPT) is a common endocrine disorder characterized by dysregulation of parathyroid hormone release. 30475215 2019
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism (PHPT) is a common endocrine disorder, resulting from the autonomous production of parathyroid hormone from 1 or more abnormal parathyroid glands. 31255197 2019
Entrez Id: 2768
Gene Symbol: GNA12
GNA12
0.020 Biomarker disease BEFREE Primary hyperparathyroidism (PHP), gastroenteropancreatic neuroendocrine tumour (GEP-NET), and pituitary adenoma (PA) developed in 90%, 52%, and 47% of patients, respectively. 31274185 2019
Entrez Id: 2896
Gene Symbol: GRN
GRN
0.020 Biomarker disease BEFREE Primary hyperparathyroidism (PHP), gastroenteropancreatic neuroendocrine tumour (GEP-NET), and pituitary adenoma (PA) developed in 90%, 52%, and 47% of patients, respectively. 31274185 2019
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
0.040 Biomarker disease BEFREE Primary hyperparathyroidism and parathyroid hormone-related protein. 8060769 1994
Entrez Id: 5741
Gene Symbol: PTH
PTH
0.200 Biomarker disease BEFREE Primary hyperparathyroidism is excluded by the immunoradiometric assay for parathyroid hormone, which is suppressed. 8060769 1994