| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | disease | BEFREE | Novel neuroimaging findings were two patients had typical neuroimaging abnormalities of CJD and frontotemporal dementia, respectively. | 29569252 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | Mutational analysis of PRNP in Alzheimer's disease and frontotemporal dementia in China. | 27910931 | 2016 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | To evaluate the proton magnetic resonance (MR) spectroscopy ((1) H MRS) changes in carriers of a novel octapeptide repeat insertion in the prion protein gene (PRNP) and family history of frontotemporal dementia with ataxia. | 22612156 | 2013 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The V363I variation was associated with frontotemporal dementia only in the proband which was also homozygous for the A allele of the progranulin single-nucleotide polymorphism rs9897526 and for methionine at codon 129 of the prion protein gene. | 21343707 | 2011 | ||||
|
0.070 | Biomarker | disease | BEFREE | This kindred has a unique combination of clinical and neuropathologic features associated with the largest base pair insertion identified to date in PRNP and underscores the need to consider familial prion disease in the differential diagnosis of a familial frontotemporal dementia-like syndrome. | 21911696 | 2011 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | We found no association between PGRN polymorphisms, APOE and microtubule-associated protein tau genotypes, and age at onset of the disease; whereas we report evidence for an association between PRNP codon 129 polymorphism and age at onset of disease in frontotemporal dementia-PGRN(+) patients. | 20711061 | 2011 | ||||
|
0.070 | Biomarker | disease | BEFREE | Variably protease-sensitive prionopathy (VPSPr) is a novel disease involving the prion protein (PrP) that has clinical similarities with non-Alzheimer's dementias especially frontotemporal dementia, diffuse Lewis body disease, and normal pressure hydrocephalus. | 21584652 | 2011 |